RSS
- You are here:
- Research Repository UCD
- >
- College of Health and Agricultural Sciences
- >
- School of Medicine
- >
- Browsing School of Medicine by Date published
JavaScript is disabled for your browser. Some features of this site may not work without it.
Browsing School of Medicine by Date published
Now showing items 1-20 of 191
-
(Elsevier, 2003-02-01)Endothelium-dependent vasodilation is thought to be mediated primarily by the NO/cGMP signaling pathway whereas cAMP-elevating vasodilators are considered to act independent of the endothelial cell layer. However, recent ...
-
(Elsevier, 2004-04)Cardiac fibroblasts regulate tissue repair and remodeling in the heart. To quantify transcript levels in these cells we performed a comprehensive gene expression study using serial analysis of gene expression (SAGE). Among ...
-
(Elsevier, 2004-10-15)Background: There is little information of the prevalence of personality disorder (PD) in those with depressive disorder in community samples; neither is there any data on the impact of PD on service utilisation or outcome ...
-
(Dental Anthropology Association, 2005)Determining sex and age in human remains is necessary to achieve positive identification of individuals in forensic settings, and to provide data required for demographic analyses in archaeological samples. Due to their ...
-
The NO/cGMP pathway inhibits Rap 1 activation in human platelets via cGMP-dependent protein kinase I (Schatteur, 2005-02)The NO/cGMP signalling pathway strongly inhibits agonist-induced platelet aggregation. However, the molecular mechanisms involved are not completely defined. We have studied NO/cGMP effects on the activity of Rap 1, an ...
-
(American Society of Hematology, 2005-04-15)The Ras-like guanine-nucleotide-binding protein Rap1 controls integrin alpha(IIb)beta3 activity and platelet aggregation. Recently, we have found that Rap1 activation can be blocked by the nitric oxide/cyclic guanosine ...
-
(Royal College of Psychiatrists, 2006)Background: Little is known about patterns of healthcare use by people with depression in Europe. Aims: To examine the use and cost of services by adults with depressive or adjustment disorders in five European countries, ...
-
(Royal College of Psychiatrists, 2006)Background: Very few studies have examined the cross-national prevalence of suicidal ideation in the general population or variables associated with it. Aims: To examine the risk factors for suicidal ideas in the general ...
-
(Elsevier, 2006-06)Background: No large-scale epidemiological study has included adjustment disorders (AD) for consideration yet it is considered to be a common psychiatric diagnosis. Methods:Using a two stage screening method, those above ...
-
(Radiological Society of North America, 2007-01)Purpose: To define the interpretative performance of radiologists experienced in computed tomographic (CT) colonography and to compare it with that of novice observers who had undergone directed training, with colonoscopy ...
-
(Oxford University Press, 2007-02)Background: Dnmt3L, a member of the DNA methyltransferase 3 family, lacks enzymatic activity but is required for de-novo methylation of imprinted genes in oocytes and for transposon repression in male germ cells. Methods: ...
-
(Elsevier, 2007-04)Individuals with personality disorders (especially paranoid personality disorder) tend to be reluctant to engage in treatment. This paper aimed to elucidate the role of personality disorder in predicting engagement with ...
-
(American Society for Biochemistry and Molecular Biology, 2007-05-04)Phosphodiesterase type 2A (PDE2A) hydrolyzes cyclic nucleotides cAMP and cGMP, thus efficiently controlling cNMP-dependent signaling pathways. PDE2A is composed of an amino-terminal region, two regulatory GAF domains, and ...
-
(Elsevier, 2007-10)The aim of this paper is to present the development of a synthetic phantom that can be used for the selection of optimal scanning parameters in computed tomography (CT) colonography. In this paper we attempt to evaluate ...
-
(American Society for Biochemistry and Molecular Biology, 2008-01-25)GTPase-activating proteins are required to terminate signaling by Rap1, a small guanine nucleotide-binding protein that controls integrin activity and cell adhesion. Recently, we identified Rap1GAP2, a GTPase-activating ...
-
(D. Steinkopff-Verlag (Springer), 2008-04)Background: Suicidal ideation is believed to be part of a constellation of suicidal behaviours that culminates in suicide. There is little information on the cross-national prevalence of all suicidal ideation or of serious ...
-
(PLOS, 2008-06)Sequencing by hybridisation is an effective method for obtaining large amounts of DNA sequence information at low cost. The efficiency of SBH depends on the design of the probe library to provide the maximum information ...
-
(Karger, 2009)Background: The volume of research involving adjustment disorder (AD) is limited. The scientific neglect of AD seems to result from the inadequate operationalisation of AD in DSM-IV and ICD-10. The aims of the present ...
-
(Elsevier, 2009-02-15)The aryl hydrocarbon receptor (AHR) is a major transcription factor regulated by different mechanisms. The classical view of AHR activation by xenobiotics needs to be amended by recent findings on the regulation of AHR by ...
-
(SPIE, 2009-03-12)Current ultrasound assessment of placental calcification relies on Grannum grading. The aim of this study was to assess if this method is reproducible by measuring inter- and intra-observer variation in grading placental ...
Now showing items 1-20 of 191