RSS
- You are here:
- Research Repository UCD
- >
- Institutes and Centres
- >
- Systems Biology Ireland
- >
- Search
JavaScript is disabled for your browser. Some features of this site may not work without it.
Search
Search Results for Collection: Systems Biology Ireland
Now showing items 1-8 of 8
-
(The Company of Biologists, 2012-02-10)Upregulation of the extracellular signal-regulated kinase (ERK) pathway has been shown to contribute to tumour invasion and progression. Because the two predominant ERK isoforms (ERK1 and ERK2, also known as MAPK3 and ...
-
(Landes Bioscience, 2011-07-01)Negative feedback is an ubiquitous feature of biological networks. Recent work from Sturm and colleaguespresents experimental evidence that biological negative feedback can serve the same function as it does for engineered ...
-
(Springer (Biomed Central Ltd.), 2012)Background: Cell-to-cell variability in protein expression can be large, and its propagation through signaling networks affects biological outcomes. Here, we apply deterministic and probabilistic models and biochemical ...
-
(Public Library of Science, 2011-11-16)Numerous unimolecular, genetically-encoded Förster Resonance Energy Transfer (FRET) probes for monitoring biochemical activities in live cells have been developed over the past decade. As these probes allow for collection ...
-
(The Royal Society of Chemistry, 2012)The abundance of a particular protein varies both over time within a single mammalian cell and between cells of a genetically identical population. Here, we investigate the properties of such noisy protein expression in ...
-
(Elsevier, 2009-08)Although endocytosis has traditionally been understood as a signal attenuation mechanism, an emerging view considers endocytosis as an integral part of signal propagation and processing. On the short time scale, trafficking ...
-
(PLOS, 2014-01-27)Western blot data are widely used in quantitative applications such as statistical testing and mathematical modelling. To ensure accurate quantitation and comparability between experiments, Western blot replicates must be ...
-
(The Royal Society, 2014-06-25)We show theoretically and experimentally a mechanism behind the emergence of wide or bimodal protein distributions in biochemical networks with nonlinear input–output characteristics (the dose–response curve) and variability ...
Now showing items 1-8 of 8