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Search Results for Collection: Systems Biology Ireland
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(Elsevier, 2010-06)The quantitative analysis of biochemical reactions and metabolites is at frontier of biological sciences. The recent availability of high-throughput technology data sets in biology has paved the way for new modelling ...
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(Discovery Medicine, 2010-03-14)Adult mesenchymal stem cells (MSCs) are non-hematopoietic cells with multi-lineage potential to differentiate into various tissues of mesodermal origin. They can be isolated from bone marrow and other tissues and have the ...
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(Springer (Biomed Central Ltd.), 2010)Mesenchymal stem cells have a natural tropism for tumours and their metastases, and are also considered immunoprivileged. This remarkable combination of properties has formed the basis for many studies investigating their ...
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(Elsevier, 2010-01)In the absence of any ideal gene delivery carrier despite the recent explosion of novel carrier systems, the current trend is to explore the complementary synergy promised by a combination of delivery systems such as ...
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(Springer-Verlag, 2010-01-20)Bone marrow-derived mesenchymal stem cells (MSCs) are known to specifically migrate to and engraft at tumour sites. Understanding interactions between cancer cells and MSCs has become fundamental to determining whether ...
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(American Association for the Advancement of Science, 2010-08-25)Clinical proteomics has yielded some early positive results—the identification of potential disease biomarkers—indicating the promise for this analytical approach to improve the current state of the art in clinical practice. ...
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(Thomson Reuters, 2010-12)Ras proteins are key elements in the regulation of cellular proliferation, differentiation and survival. Mutational activation of Ras or of components of its effector pathways are detected in one-third of human cancers and ...
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(Springer (Biomed Central Ltd.), 2010)Background: The purpose of this manuscript is to provide, based on an extensive analysis of a proteomic data set, suggestions for proper statistical analysis for the discovery of sets of clinically relevant biomarkers. As ...
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(IOP Publishing, 2010-10-27)Micro-organisms living in a turbulent fluid environment often use directed motility to locate regions of higher than average nutrient concentrations. Here, we consider a simple continuum model for the distribution of such ...
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(Mary Ann Liebert, 2010-09)