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Search Results for Collection: Systems Biology Ireland
Now showing items 1-5 of 5
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(Springer-Verlag, 2011-11-09)The oxygen-sensitive transcription factor hypoxia inducible factor (HIF) is a key regulator of gene expression during adaptation to hypoxia. Crucially, inflamed tissue often displays regions of prominent hypoxia. Recent ...
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(American Society for Biochemistry and Molecular Biology, 2012-03-06)Carbon dioxide (CO2) is increasingly being appreciated as an intracellular signaling molecule that affects inflammatory and immune responses. Elevated arterial CO2 (hypercapnia) is encountered in a range of clinical ...
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(National Academy of Sciences, 2013-10)Hypoxia is a prominent feature of chronically inflamed tissues. Oxygen-sensing hydroxylases control transcriptional adaptation to hypoxia through the regulation of hypoxia-inducible factor (HIF) and nuclear factor κB ...
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(American Society for Biochemistry and Molecular Biology, 2012-03-06)Carbon dioxide (CO2) is increasingly being appreciated as an intracellular signaling molecule that affects inflammatory and immune responses. Elevated arterial CO2 (hypercapnia) is encountered in a range of clinical ...
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(Elsevier, 2010-12)The mucosal surface of the lung is the key interface between the external atmosphere and the bloodstream. Normally, this well oxygenated tissue is maintained in state of sterility by a number of innate immune processes. ...
Now showing items 1-5 of 5