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Imaging the genetics of executive functions
Date Issued
2008-09
Date Available
2014-11-07T10:21:59Z
Abstract
Recent advances in neuroimaging technologies have allowed ever more detailed studies of the human brain. The combination of neuroimaging techniques with genetics may provide a more sensitive measure of the influence of genetic variants on cognitive function than behavioural measures alone. Here we present a review of functional magnetic resonance imaging (fMRI) studies of genetic links to executive functions, focusing on sustained attention, working memory and response inhibition. In addition to studies in the normal population, we also address findings from three clinical populations: schizophrenia, ADHD and autism spectrum disorders. While the findings in the populations studied do not always converge, they all point to the usefulness of neuroimaging techniques such as fMRI as potential endophenotypes for parsing the genetic aetiology of executive function.
Sponsorship
Health Research Board
Science Foundation Ireland
Other Sponsorship
Irish Higher Education Authority’s Programme for Research in Third-Level Institutions
Type of Material
Journal Article
Publisher
Elsevier
Journal
Biological Psychology
Volume
79
Issue
1
Start Page
30
End Page
42
Copyright (Published Version)
2007 Elsevier
Language
English
Status of Item
Peer reviewed
This item is made available under a Creative Commons License
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12._Greene_ReviewImgGen_Biological_Psychology_prepub.pdf
Size
282.33 KB
Format
Owning collection
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