Browsing by Author Kholodenko, Boris N.


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Published DateTitleAuthor(s)
31-Dec-2014Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapiesTortolina, LorenzoDuffy, David J.Maffei, MassimoCarmody, Aimee M.Kolch, WalterKholodenko, Boris N.et al.
10-Apr-2014The APC network regulates the removal of mutated cells from colonic cryptsSong, Je-HoonHuels, David J.Ridgway, Rachel A.Kholodenko, Boris N.Kolch, Walteret al.
27-Jan-2016Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility SwitchesByrne, Kate M.Monsefi, NaserDawson, John C.Degasperi, AndreaVolinsky, NataliaDobrzyński, MaciejKida, KatarzynaKolch, WalterNguyen, Lan K.Von Kriegsheim, AlexKholodenko, Boris N.et al.
15-Jan-2015Competing to coordinate cell fate decisions: the MST2-Raf-1 signaling deviceNguyen, Lan K.Matallanas, DavidRomano, DavidKholodenko, Boris N.Kolch, Walter
Oct-2016The complexities and versatility of the RAS-to-ERK signalling system in normal and cancer cellsFey, DirkMatallanas, DavidRauch, JensRukhlenko, Oleksii S.Kholodenko, Boris N.
19-Jan-2012Cross-talk between mitogenic Ras/MAPK and survival PI3K/Akt pathways: a fine balanceAksamitiene, EditaKiyatkin, Anatoly B.Kholodenko, Boris N.
22-Aug-2018Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS SignalingRukhlenko, Oleksii S.Khorsand, FahimehKrstic, AleksandarRauch, NoraFitzgibbon, ChereeMatallanas, DavidRauch, JensKolch, WalterKholodenko, Boris N.et al.
22-Sep-2015Drug Resistance Resulting from Kinase Dimerization Is Rationalized by Thermodynamic Factors Describing Allosteric Inhibitor EffectsKholodenko, Boris N.
5-Nov-2014A dynamic model of the MYCN regulated DNA damage response in NeuroblastomaKuehn, AxelKholodenko, Boris N.Fey, Dirk
29-Jul-2015DYVIPAC: an integrated analysis and visualisation framework to probe multi-dimensional biological networksNguyen, Lan K.Degasperi, AndreaCotter, PhilipKholodenko, Boris N.
Aug-2009Endocytosis and signalling: A meeting with mathematicsBirtwistle, Marc R.Kholodenko, Boris N.
27-Jan-2014Evaluating Strategies to Normalise Biological Replicates of Western Blot DataDegasperi, AndreaBirtwistle, Marc R.Volinsky, NataliaKolch, WalterKholodenko, Boris N.
Feb-2016Feedback regulation in cell signalling: Lessons for cancer therapeuticsNguyen, Lan K.Kholodenko, Boris N.
9-Dec-2014Feedforward regulation of mRNA stability by prolonged extracellular signal-regulated kinase activityNagashima, TakeshiInoue, NorihikoYumoto, NorikoVolinsky, NataliaKholodenko, Boris N.
Jul-2010Formation of Intracellular Concentration Landscapes by Multisite Protein ModificationMuñoz-García, JavierKholodenko, Boris N.Neufeld, Zoltán
27-Nov-2015Frequency modulation of ERK activation dynamics rewires cell fateRyu, HyunryulChung, MinhwanDobrzynsk, MaciejFey, DirkKholodenko, Boris N.et al.
7-Jul-2016HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC statusWeitsman, GregoryBarber, Paul R.Nguyen, Lan K.Kholodenko, Boris N.et al.
2013Integrating Bayesian variable selection with Modular Response Analysis to infer biochemical network topologySantra, TapeshKolch, WalterKholodenko, Boris N.
22-Nov-2016Integrating network reconstruction with mechanistic modeling to predict cancer therapiesHalasz, MelindaKholodenko, Boris N.Kolch, WalterSantra, Tapesh
2013It takes two to tango—signalling by dimeric Raf kinasesBaljuls, AngelaKholodenko, Boris N.Kolch, Walter