Browsing by Author Nguyen, Lan K.


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Published DateTitleAuthor(s)
27-Jan-2016Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility SwitchesByrne, Kate M.Monsefi, NaserDawson, John C.Degasperi, AndreaVolinsky, NataliaDobrzyński, MaciejKida, KatarzynaKolch, WalterNguyen, Lan K.Von Kriegsheim, AlexKholodenko, Boris N.et al.
15-Jan-2015Competing to coordinate cell fate decisions: the MST2-Raf-1 signaling deviceNguyen, Lan K.Matallanas, DavidRomano, DavidKholodenko, Boris N.Kolch, Walter
1-Mar-2011Distinct noise-controlling roles of multiple negative feedback mechanisms in a prokaryotic operon systemNguyen, Lan K.Kulasiri, D.
6-Feb-2013A dynamic model of the hypoxia-inducible factor 1 (HIF-1α) networkNguyen, Lan K.Cavadas, Miguel A. S.Scholz, Carsten C.et al.
29-Jul-2015DYVIPAC: an integrated analysis and visualisation framework to probe multi-dimensional biological networksNguyen, Lan K.Degasperi, AndreaCotter, PhilipKholodenko, Boris N.
Feb-2016Feedback regulation in cell signalling: Lessons for cancer therapeuticsNguyen, Lan K.Kholodenko, Boris N.
7-Jul-2016HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC statusWeitsman, GregoryBarber, Paul R.Nguyen, Lan K.Kholodenko, Boris N.et al.
2013Hypoxia-inducible factor (HIF) network: insights from mathematical modelsCavadas, Miguel A. S.Nguyen, Lan K.Cheong, Alex
5-Oct-2014Integrated signaling pathway and gene expression regulatory model to dissect dynamics of Escherichia coli challenged mammary epithelial cellsden Breems, Nicoline Y.Nguyen, Lan K.Kulasiri, Don
25-Jun-2014Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responsesDobrzyński, MaciejNguyen, Lan K.Birtwistle, Marc R.Kriegsheim, Alexander vonFernández, Alfonso BlancoCheong, AlexKolch, WalterKholodenko, Boris N.
8-Dec-2015Phosphorylation of RAF Kinase Dimers Drives Conformational Changes that Facilitate TransactivationJambrina, Pablo G.Rauch, NoraPilkington, RuthRybakova, KatjaNguyen, Lan K.Kholodenko, Boris N.Buchete, Nicolae-ViorelKolch, WalterRosta, Edina
24-Jan-2014Polyubiquitin chain assembly and organization determine the dynamics of protein activation and degradationNguyen, Lan K.Dobrzyńskia, MaciejFey, DirkKholodenko, Boris N.
3-Aug-2015Protein-protein interactions generate hidden feedback and feed-forward loops to trigger bistable switches, oscillations and biphasic dose-responsesVarusai, Thawfeek M.Kolch, WalterKholodenko, Boris N.Nguyen, Lan K.
14-Mar-2012Regulation of oscillation dynamics in biochemical systems with dual negative feedback loopsNguyen, Lan K.
Nov-2015Relationship between serum response factor and androgen receptor in prostate cancerPrencipe, MariaO'Neill, AmandaO'Hurley, GillianNguyen, Lan K.Fabre, AurélieGallagher, William M.Watson, R. Williamet al.
7-Oct-2016SARAH Domain-mediated MST2-RASSF Dimeric InteractionsSánchez-Sanz, GoarTywoniuk, BartłomiejMatallanas, DavidRomano, DavidNguyen, Lan K.Kholodenko, Boris N.Rosta, EdinaKolch, WalterBuchete, Nicolae-Viorel
14-Mar-2012Signalling by protein phosphatases and drug development: a systems-centred viewNguyen, Lan K.Matallanas, DavidCroucher, David R.et al.
22-Mar-2016Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling PathwaysRodriguez, JavierPilkington, RuthGarcia Munoz, AmayaNguyen, Lan K.Rauch, NoraKennedy, Susan A.Monsefi, NaserHerrero, AnaTaylor, Cormac T.Kriegsheim, Alexander von
15-Dec-2011Switches, Excitable Responses and Oscillations in the Ring1B/Bmi1 Ubiquitination SystemNguyen, Lan K.Muñoz-García, JavierMaccario, Heleneet al.
Dec-2014Ubiquitin chain specific auto-ubiquitination triggers sustained oscillation, bistable switches and excitable firingNguyen, Lan K.Zhao, QiVarusai, Thawfeek M.Kholodenko, Boris N.