Browsing by Author Kholodenko, Boris N.


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Showing results 7 to 26 of 47 < previous   next >
Published DateTitleAuthor(s)
22-Aug-2018Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS SignalingRukhlenko, Oleksii S.Khorsand, FahimehKrstic, AleksandarRauch, NoraFitzgibbon, ChereeMatallanas, DavidRauch, JensKolch, WalterKholodenko, Boris N.et al.
22-Sep-2015Drug Resistance Resulting from Kinase Dimerization Is Rationalized by Thermodynamic Factors Describing Allosteric Inhibitor EffectsKholodenko, Boris N.
5-Nov-2014A dynamic model of the MYCN regulated DNA damage response in NeuroblastomaKuehn, AxelKholodenko, Boris N.Fey, Dirk
29-Jul-2015DYVIPAC: an integrated analysis and visualisation framework to probe multi-dimensional biological networksNguyen, Lan K.Degasperi, AndreaCotter, PhilipKholodenko, Boris N.
Aug-2009Endocytosis and signalling: A meeting with mathematicsBirtwistle, Marc R.Kholodenko, Boris N.
27-Jan-2014Evaluating Strategies to Normalise Biological Replicates of Western Blot DataDegasperi, AndreaBirtwistle, Marc R.Volinsky, NataliaKolch, WalterKholodenko, Boris N.
Feb-2016Feedback regulation in cell signalling: Lessons for cancer therapeuticsNguyen, Lan K.Kholodenko, Boris N.
9-Dec-2014Feedforward regulation of mRNA stability by prolonged extracellular signal-regulated kinase activityNagashima, TakeshiInoue, NorihikoYumoto, NorikoVolinsky, NataliaKholodenko, Boris N.
Jul-2010Formation of Intracellular Concentration Landscapes by Multisite Protein ModificationMuñoz-García, JavierKholodenko, Boris N.Neufeld, Zoltán
27-Nov-2015Frequency modulation of ERK activation dynamics rewires cell fateRyu, HyunryulChung, MinhwanDobrzynsk, MaciejFey, DirkKholodenko, Boris N.et al.
7-Jul-2016HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC statusWeitsman, GregoryBarber, Paul R.Nguyen, Lan K.Kholodenko, Boris N.et al.
1-Nov-2018Impact of measurement noise, experimental design, and estimation methods on Modular Response Analysis based network reconstructionThomaseth, CaterinaFey, DirkSantra, TapeshRukhlenko, Oleksii S.Radde, Nicole E.Kholodenko, Boris N.
2013Integrating Bayesian variable selection with Modular Response Analysis to infer biochemical network topologySantra, TapeshKolch, WalterKholodenko, Boris N.
22-Nov-2016Integrating network reconstruction with mechanistic modeling to predict cancer therapiesHalasz, MelindaKholodenko, Boris N.Kolch, WalterSantra, Tapesh
Oct-2019An Integrative Computational Approach for a Prioritization of Key Transcription Regulators Associated With Nanomaterial-Induced ToxicityZhernovkov, VadimSantra, TapeshCassidy, HilaryRukhlenko, Oleksii S.Matallanas, DavidKrstic, AleksandarKolch, WalterLobaskin, VladimirKholodenko, Boris N.
2013It takes two to tango—signalling by dimeric Raf kinasesBaljuls, AngelaKholodenko, Boris N.Kolch, Walter
Dec-2016MAPK kinase signalling dynamics regulate cell fate decisions and drug resistanceRauch, NoraRukhlenko, Oleksii S.Kolch, WalterKholodenko, Boris N.
12-Jun-2015Mitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant TransformationMilewska, MalgorzataRomano, DavidHerrero, AnaGuerriero, Maria LuisaKholodenko, Boris N.Kolch, Walter
13-Feb-2014Navigating the Multilayered Organization of Eukaryotic Signaling: A New Trend in Data IntegrationSantra, TapeshKolch, WalterKholodenko, Boris N.
25-Jun-2014Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responsesDobrzyński, MaciejNguyen, Lan K.Birtwistle, Marc R.Kriegsheim, Alexander vonFernández, Alfonso BlancoCheong, AlexKolch, WalterKholodenko, Boris N.