Browsing by Author Kholodenko, Boris N.


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Showing results 23 to 42 of 47 < previous   next >
Published DateTitleAuthor(s)
Dec-2016MAPK kinase signalling dynamics regulate cell fate decisions and drug resistanceRauch, NoraRukhlenko, Oleksii S.Kolch, WalterKholodenko, Boris N.
12-Jun-2015Mitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant TransformationMilewska, MalgorzataRomano, DavidHerrero, AnaGuerriero, Maria LuisaKholodenko, Boris N.Kolch, Walter
13-Feb-2014Navigating the Multilayered Organization of Eukaryotic Signaling: A New Trend in Data IntegrationSantra, TapeshKolch, WalterKholodenko, Boris N.
25-Jun-2014Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responsesDobrzyński, MaciejNguyen, Lan K.Birtwistle, Marc R.Kriegsheim, Alexander vonFernández, Alfonso BlancoCheong, AlexKolch, WalterKholodenko, Boris N.
12-Oct-2016On the personalised modelling of cancer signallingFey, DirkKuehn, AxelKholodenko, Boris N.
8-Dec-2015Phosphorylation of RAF Kinase Dimers Drives Conformational Changes that Facilitate TransactivationJambrina, Pablo G.Rauch, NoraPilkington, RuthRybakova, KatjaNguyen, Lan K.Kholodenko, Boris N.Buchete, Nicolae-ViorelKolch, WalterRosta, Edina
Sep-2010PI3K/Akt-sensitive MEK-independent compensatory circuit of ERK activation in ER-positive PI3K-mutant T47D breast cancer cellsAksamitiene, EditaKholodenko, Boris N.Kolch, Walteret al.
24-Jan-2014Polyubiquitin chain assembly and organization determine the dynamics of protein activation and degradationNguyen, Lan K.Dobrzyńskia, MaciejFey, DirkKholodenko, Boris N.
20-Mar-2009Positional Information Generated by Spatially Distributed Signaling CascadesMuñoz-García, JavierNeufeld, ZoltánKholodenko, Boris N.et al.
21-Oct-2016Probing the Heterogeneity of Protein Kinase Activation in Cells by Super-resolution MicroscopyZhang, RuobingFruhwirth, Gilbert O.Coban, OanaKholodenko, Boris N.et al.
3-Aug-2015Protein-protein interactions generate hidden feedback and feed-forward loops to trigger bistable switches, oscillations and biphasic dose-responsesVarusai, Thawfeek M.Kolch, WalterKholodenko, Boris N.Nguyen, Lan K.
1-Jun-2018Reconstructing static and dynamic models of signaling pathways using Modular Response AnalysisSantra, TapeshRukhlenko, Oleksii S.Zhernovkov, VadimKholodenko, Boris N.
7-Oct-2016SARAH Domain-mediated MST2-RASSF Dimeric InteractionsSánchez-Sanz, GoarTywoniuk, BartłomiejMatallanas, DavidRomano, DavidNguyen, Lan K.Kholodenko, Boris N.Rosta, EdinaKolch, WalterBuchete, Nicolae-Viorel
22-Dec-2015Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patientsFey, DirkHalasz, MelindaDreidax, DanielKennedy, Sean P.Rauch, NoraGarcia Munoz, AmayaPilkington, RuthFischer, MatthiasKolch, WalterKholodenko, Boris N.Croucher, David R.et al.
Jun-2010Signalling ballet in space and timeKholodenko, Boris N.Hancock, John F.Kolch, Walter
1-Apr-2015Signalling mechanisms regulating phenotypic changes in breast cancer cellsVolinsky, NataliaMcCarthy, Cormac J.Kriegsheim, Alexander vonSaban, NinaOkada-Hatakeyama, MarikoKolch, WalterKholodenko, Boris N.
1-Oct-2010Signalling over a distance: gradient patterns and phosphorylation waves within single cellsMuñoz-García, JavierKholodenko, Boris N.
Dec-2009Spatially distributed cell signallingKholodenko, Boris N.
Feb-2014Systems biology embedded target validation: improving efficacy in drug discoveryVandamme, DriekeMinke, Benedikt A.Fitzmaurice, WilliamKholodenko, Boris N.Kolch, Walter
30-Jul-2013Systems medicine: helping us understand the complexity of diseaseVandamme, DriekeFitzmaurice, WilliamKholodenko, Boris N.et al.