Options
Degasperi, Andrea
Preferred name
Degasperi, Andrea
Official Name
Degasperi, Andrea
Research Output
Now showing 1 - 1 of 1
- PublicationA process algebra framework for multi-scale modelling of biological systemsWe introduce a novel process algebra for modelling biological systems at multiple scales, called process algebra with hooks (PAH). Processes represent biological entities, such as molecules, cells and tissues, while two algebraic operators, both symmetric, define composition of processes within and between scales. Composed actions allow for biological events to interact within and between scales at the same time. The algebra has a stochastic semantics based on functional rates of reactions. Two bisimulations are defined on PAH processes. The first bisimulation is used to aid model development by checking that two biological scales can interact correctly. The second bisimulation is a congruence that relates models, or part of models, that can perform the same timed events at a specified scale. Finally, we provide a PAH model of pattern formation in a tissue and illustrate reasoning about its behaviour using the PAH framework.
261Scopus© Citations 1