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Hahne, Hannes
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Hahne, Hannes
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Hahne, Hannes
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- PublicationDMSO enhances electrospray response, boosting sensitivity of proteomic experiments(Nature Publishing Group, 2013-10)
; ; ; ; We report that low percentages of dimethylsulfoxide (DMSO) in liquid chromatography solvents lead to a strong enhancement of electrospray ionization of peptides, improving the sensitivity of protein identification in bottom-up proteomics by up to tenfold. The method can be easily implemented on any LC-MS/MS system without modification to hardware or software and at no additional cost.1152Scopus© Citations 191