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Muldoon, Jimmy
Preferred name
Muldoon, Jimmy
Official Name
Muldoon, Jimmy
Research Output
Now showing 1 - 2 of 2
- PublicationPreparation of iminosugars from aminopolyols via selective oxidation using galactose oxidase(Royal Society of Chemistry (RSC), 2022-11-07)
; ; ; Minimally protected aminopolyols are novel substrates for the galactose oxidase variant F2. Site-selective oxidation proceeds at the terminal primary alcohol, followed by spontaneous cyclisation to afford stable hemiaminal/hemiacetal anomers of the piperidine and azepane scaffolds, with isolated yields of up to 94%. Simultaneous deprotection and reduction occured readily to afford valuable and biologically relevant iminosugars.34Scopus© Citations 1 - PublicationA convenient and mild chromatography-free method for the purification of the products of Wittig and Appel reactions(RSC Publishing, 2012-03)
; ; ; A mild method for the facile removal of phosphine oxide from the crude products of Wittig and Appel reactions is described. Work-up with oxalyl chloride to generate insol. chlorophosphonium salt (CPS) yields phosphorus-free products for a wide variety of these reactions. The CPS product can be further converted into phosphine.Scopus© Citations 76 1316