Now showing 1 - 3 of 3
  • Publication
    Investigating the Need for Pediatric-Specific Automatic Seizure Detection
    (IEEE, 2022-12-03) ;
    Approximately 1 in every 150 children is diagnosed with epilepsy during the first ten years of life [1]. These children experience seizures, which disrupt their lives and directly harm the developing brain. Electroencephalography (EEG) is the main tool used clinically to diagnose seizures and epilepsy. However, the interpretation of EEGs requires time-consuming expert analysis [2]. Automated detection systems are a powerful tool that can help address the issue by reducing expert annotation time. Research on the automatic detection of seizures in pediatric EEG has been limited. Most seizure detection methods have been developed and tested using larger numbers of adult EEG [3], [4]. However, research has shown that brain events in EEG change with ageing [5], [6]. Therefore, model trained on EEGs from adults may not be be suitable for children. To test this hypothesis, we trained a seizure detection model on adult EEG and tested on adult and pediatric EEG recordings.
      57Scopus© Citations 2
  • Publication
    XGboost-based Method for Seizure Detection in Mouse Models of Epilepsy
    Epilepsy is a chronic neurological disease which affects over 50 million people worldwide [1], caused by the disruption of the finely tuned inhibitory and excitatory balance in brain networks, manifesting clinically as seizures. Electroencephalographic (EEG) monitoring in rodent disease models of epilepsy is critical in the understanding of disease mechanisms and the development of anti-seizure drugs. However, the visual annotation of EEG traces is time-consuming, and is complicated by different models and seizure types. Automated annotation systems can help to solve these problems by reducing expert annotation time and increasing the throughput and reliability of seizure quantification. As machine learning is becoming increasingly popular for modelling sequential signals such as EEG, several researchers have tried machine learning to detect seizures in EEG traces from mouse models of epilepsy. Most existing work [2], [3] can only detect seizures in single mouse models of epilepsy and research on multiple mouse models has been limited to-date.
      79Scopus© Citations 1
  • Publication
    Epileptic Seizure Detection in Clinical EEGs Using an XGboost-based Method
    (IEEE, 2020-12-05) ;
    Epilepsy is one of the most common serious disorders of the brain, affecting about 50 million people worldwide. Electroencephalography (EEG) is an electrophysiological monitoring method which is used to measure tiny electrical changes of the brain, and it is frequently used to diagnose epilepsy. However, the visual annotation of EEG traces is time-consuming and typically requires experienced experts. Therefore, automatic seizure detection can help to reduce the time required to annotate EEGs. Automatic detection of seizures in clinical EEGs has been limited-to date. In this study, we present an XGBoost-based method to detect seizures in EEGs from the TUH-EEG Corpus. 4,597 EEG files were used to train the method, 1,013 EEGs were used as a validation set, and 1,026 EEG files were used to test the method. Sixty-four features were selected as the input to the training set, and Synthetic Minority Over-sampling Technique was used to balance the dataset. Our XGBoost-based method achieved sensitivity and false alarm/24 hours of 20.00% and 15.59, respectively, in the test set. The proposed XGBoost-based method has the potential to help researchers automatically analyse seizures in clinical EEG recordings.
      146Scopus© Citations 13