Options
Stephens, Niamh
Preferred name
Stephens, Niamh
Official Name
Stephens, Niamh
Research Output
Now showing 1 - 1 of 1
- PublicationVersatility of enzymes catalyzing late steps in polyene 67-121C biosynthesisActinoplanes caeruleus produces 67-121C, a heptaene macrolide modified with a D-mannosyl-D-mycosaminyl disaccharide. Draft genome sequencing revealed genes encoding mycosaminyltransferase, mycosamine synthase, a cytochrome P450 that modifies the macrolactone core, and the extending mannosyltransferase. Only the mycosamine synthase and P450 were active in the biosynthesis of amphotericins in Streptomyces nodosus, the amphotericin producer.
Scopus© Citations 13 400