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Exploration of the Generation and Suppression of Pathological Oscillatory Neural Activity in a Model of Deep Brain Stimulation in Parkinsons disease
Date Issued
2015-01-17
Date Available
2016-12-01T13:01:10Z
Abstract
This study explores possible mechanisms for the generation of pathological neural oscillatory activity associated with Parkinson’s disease in theoretical models. The suppression of the model oscillations with high frequency stimulation, analogous to the use of deep brain stimulation (DBS) in the treatment of Parkinson's disease, is also examined. The relationship between oscillation amplitude and the amplitude of the applied stimulation is explored theoretically and then compared with experimental data recorded in patients.
Sponsorship
Science Foundation Ireland
Type of Material
Conference Publication
Language
English
Status of Item
Peer reviewed
Conference Details
21st Bioengineering in Ireland Conference (BINI) 2015, Carton House, Maynooth, Co. Kildare, Ireland, 16-17 January 2015
This item is made available under a Creative Commons License
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