Repository logo
  • Log In
    New user? Click here to register.Have you forgotten your password?
University College Dublin
  • Colleges & Schools
  • Statistics
  • All of DSpace
  • Log In
    New user? Click here to register.Have you forgotten your password?
  1. Home
  2. College of Health and Agricultural Sciences
  3. School of Public Health, Physiotherapy and Sports Science
  4. Public Health, Physiotherapy and Sports Science Research Collection
  5. Self-directed home-based neuromuscular electrical stimulation (NMES) in patients with advanced cancer and poor performance status: a feasibility study
 
  • Details
Options

Self-directed home-based neuromuscular electrical stimulation (NMES) in patients with advanced cancer and poor performance status: a feasibility study

File(s)
FileDescriptionSizeFormat
Download 12 DOConnor Self-Directed Home-Based Neuromuscular eletrical stimulation in patients.pdf688.44 KB
Author(s)
O'Connor, Dominic 
Lennon, Olive 
Wright, Sarah 
Caulfield, Brian 
Uri
http://hdl.handle.net/10197/11629
Date Issued
16 March 2020
Date Available
16T11:53:52Z October 2020
Abstract
Purpose: Concurrent neuromuscular electrical stimulation (NMES) involving sub-tetanic low frequency and tetanic high frequency which targets aerobic and muscular fitness is a potential alternative to conventional exercise in cancer rehabilitation. However, its safety and feasibility in patients with advanced cancer are unknown. The aim of this feasibility study was to determine safety and feasibility and evaluate changes in functional and health-related quality of life (HR-QoL) outcomes in individuals with advanced cancer and poor performance status after concurrent NMES. These results should help inform the design of future studies. Methods: Participants with advanced cancer and poor performance status (Eastern Cooperative Oncology Group scale ≥ 2) (n = 18) were recruited. The intervention included a novel NMES intervention implemented over a 4-week period. Functional exercise capacity, lower limb muscle endurance and HR-QoL were measured by 6-min walk test (6MWT), 30-s sit-to-stand (30STS) and European Organization for Research and Treatment quality of life questionnaire core-30 (EORTC QLQ C30) pre and post-intervention. Participants unable to complete the 6-min walk test completed the timed up and go test. Participant experience and the impact of the intervention on daily life were investigated through semi-structured interviews. Results: Ten of 18 participants completed the intervention. No adverse events were reported. Seven of 8 participants improved 6MWT performance (2 of 2 improved timed up and go), 8 of 10 participants improved 30STS and 8 of 10 participants improved Global quality of life. Perceived benefits included improved mobility and muscle strength. Conclusions: Neuromuscular electrical stimulation appears safe and feasible in advanced cancer and may improve physical and HR-QoL outcomes. Future prospective trials are warranted to confirm these findings prior to clinical implementation in an advanced cancer setting.
Sponsorship
European Commission Horizon 2020
Type of Material
Journal Article
Publisher
Springer
Journal
Supportive Care in Cancer
Volume
28
Start Page
5529
End Page
5536
Copyright (Published Version)
2020 the Authors
Keywords
  • Oncology

  • Rehabilitation

  • NMES

  • Neuromuscular electri...

  • Advanced cancer

  • Sit-to-stand

  • Physical function

  • Physical activity

  • Exercise

  • Adults

  • COPD

DOI
10.1007/s00520-020-05394-0
Language
English
Status of Item
Peer reviewed
ISSN
0941-4355
This item is made available under a Creative Commons License
https://creativecommons.org/licenses/by-nc-nd/3.0/ie/
Owning collection
Public Health, Physiotherapy and Sports Science Research Collection
Scopus© citations
3
Acquisition Date
Feb 5, 2023
View Details
Views
545
Last Month
1
Acquisition Date
Feb 5, 2023
View Details
Downloads
134
Acquisition Date
Feb 5, 2023
View Details
google-scholar
University College Dublin Research Repository UCD
The Library, University College Dublin, Belfield, Dublin 4
Phone: +353 (0)1 716 7583
Fax: +353 (0)1 283 7667
Email: mailto:research.repository@ucd.ie
Guide: http://libguides.ucd.ie/rru

Built with DSpace-CRIS software - Extension maintained and optimized by 4Science

  • Cookie settings
  • Privacy policy
  • End User Agreement