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  5. Structure-activity relationship of a novel family of cysteinyl leukotriene receptor antagonist quinoline compounds with anti-angiogenic activity
 
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Structure-activity relationship of a novel family of cysteinyl leukotriene receptor antagonist quinoline compounds with anti-angiogenic activity

Author(s)
Reynolds, Alison  
Ventosa, Pilar  
Granander, Johan  
Kilty, Claire  
Young, Elizabeth  
Butler, Clare T.  
Galvin, Orla  
Merrigan, Stephanie  
Sasore, Temitope  
Fernandez, Yolanda  
Gilheany, Declan G.  
Kennedy, Breandán  
Uri
http://hdl.handle.net/10197/12596
Date Issued
2017-04-01
Date Available
2021-11-09T13:09:19Z
Abstract
Introduction: Previously, we identified quininib (2-[(E)-2-(quinolin-2-yl)vinyl]phenol), a cysteinyl leukotriene receptor antagonist with anti-angiogenic and anti-permeable activity (1,2). Here, we report a structure activity relationship study to more comprehensively characterise features which confer anti-angiogenic activity.
Type of Material
Conference Publication
Publisher
British Pharmacological Society
Journal
pA2 Online
Volume
16
Issue
1
Subjects

Cysteinyl leukotriene...

Anti-angiogenic activ...

Blindness

Cancer

Arthritis

Quinoline compounds

Web versions
http://www.pa2online.org/abstract/abstract.jsp?abid=33289
Language
English
Status of Item
Peer reviewed
Conference Details
Pharacology 2016, London, United Kingdom, 13-15 December 2016
ISSN
1741-1157
This item is made available under a Creative Commons License
https://creativecommons.org/licenses/by-nc-nd/3.0/ie/
File(s)
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Pharmacology_2016_vol16issue1abst200p.pdf

Size

15.13 KB

Format

Adobe PDF

Checksum (MD5)

9689d10ce000377053272b5f03019514

Owning collection
Veterinary Medicine Research Collection

Item descriptive metadata is released under a CC-0 (public domain) license: https://creativecommons.org/public-domain/cc0/.
All other content is subject to copyright.

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