Options
Problems, challenges and promises: perspectives on precision medicine
Author(s)
Date Issued
2015-08
Date Available
2016-08-05T01:00:11Z
Abstract
The 'precision medicine (systems medicine)' concept promises to achieve a shift to future healthcare systems with a more proactive and predictive approach to medicine, where the emphasis is on disease prevention rather than the treatment of symptoms. The individualization of treatment for each patient will be at the centre of this approach, with all of a patient’s medical data being computationally integrated and accessible. Precision medicine is being rapidly embraced by biomedical researchers, pioneering clinicians and scientific funding programmes in both the European Union (EU) and USA. Precision medicine is a key component of both Horizon 2020 (the EU Framework Programme for Research and Innovation) and the White House’s Precision Medicine Initiative. Precision medicine promises to revolutionize patient care and treatment decisions. However, the participants in precision medicine are faced with a considerable central challenge. Greater volumes of data from a wider variety of sources are being generated and analysed than ever before; yet, this heterogeneous information must be integrated and incorporated into personalized predictive models, the output of which must be intelligible to non-computationally trained clinicians. Drawing primarily from the field of ‘oncology’, this article will introduce key concepts and challenges of precision medicine and some of the approaches currently being implemented to overcome these challenges. Finally, this article also covers the criticisms of precision medicine overpromising on its potential to transform patient care.
Sponsorship
European Commission - Seventh Framework Programme (FP7)
Science Foundation Ireland
Type of Material
Journal Article
Publisher
Oxford University Press
Journal
Briefings in Bioinformatics
Start Page
1
End Page
11
Copyright (Published Version)
2015 the Author
Language
English
Status of Item
Peer reviewed
This item is made available under a Creative Commons License
File(s)
No Thumbnail Available
Name
Problems, Challenges and Promises Perspectives on Precision Medicine.pdf
Size
543.21 KB
Format
Owning collection
Scopus© citations
91
Acquisition Date
Mar 28, 2024
Mar 28, 2024
Views
1866
Last Month
1
1
Acquisition Date
Mar 27, 2024
Mar 27, 2024
Downloads
610
Last Week
2
2
Last Month
13
13
Acquisition Date
Mar 27, 2024
Mar 27, 2024