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  5. Theoretical framework for nanoparticle uptake and accumulation kinetics in dividing cell populations
 
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Theoretical framework for nanoparticle uptake and accumulation kinetics in dividing cell populations

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Author(s)
Ã…berg, Christoffer 
Kim, Jong Ah 
Salvati, Anna 
Dawson, Kenneth A. 
Uri
http://hdl.handle.net/10197/4570
Date Issued
February 2013
Date Available
12T09:04:32Z September 2013
Abstract
Nano-sized objects interact with biological systems in fundamentally novel ways, thereby holding great promise for targeted drug delivery. It has also been suggested they could constitute a hitherto unseen hazard. Numerous experimental studies in the field are taking place. We consider that the nature of the interactions allows a more fundamental theoretical framework to be developed. In particular, we describe the intimate link that develops between nanoparticle uptake and cell population evolution. Explicit analytical results are given and the theory compared to experimental observations.
Type of Material
Journal Article
Publisher
IOP Science
Journal
EPL : Europhysics Letters
Volume
101
Issue
3
Start Page
38007
Copyright (Published Version)
EPLA, 2013
Keywords
  • Molecule-cell interac...

  • Targeted drug deliver...

  • Cell population evolu...

  • Nanoparticle-cell int...

DOI
10.1209/0295-5075/101/38007
Language
English
Status of Item
Peer reviewed
This item is made available under a Creative Commons License
https://creativecommons.org/licenses/by-nc-nd/3.0/ie/
Owning collection
Chemistry Research Collection
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28
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Jan 31, 2023
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