In this New Technologies Issue of Current Opinion in Pharmacology, we were tasked with finding a set of articles of interest to readers on the topic of combination technologies involving drug delivery and medical devices, with an emphasis on pharmacological aspects. Most of the authors are experts in biomaterials and understand how they can be used in devices. Yet, they all pay attention to pharmacology since the technologies they are developing are designed to fulfil an unmet therapeutic need in terms of localising a molecule to a region in the body, thereby reducing toxicity and improving PK/pharmacodynamics (PD), or of causing an optimised controlled release profile of a molecule in the systemic circulation to improve efficacy, reduce side effects, or to address compliance issues.
