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Methyltransferase Activity of an Iridium Center with Methylpyridinium as Methylene Source
Date Issued
2011-10-10
Date Available
2015-08-20T16:05:26Z
Abstract
An iridium center transfers a methyl group from pyridinium to an aryl unit, using exclusively the pyridine-bound methyl group as a mild methylene source. The reaction also involves cleavage of an unactivated C(aryl)[BOND]H bond and nitrile solvent activation. The process is reminiscent of DNA methylation and entails the formation of two new C(sp2)[BOND]C(sp3) bonds within the metal coordination sphere (see scheme).
Sponsorship
European Research Council
Science Foundation Ireland
Type of Material
Journal Article
Publisher
Wiley
Journal
Angewandte Chemie International Edition
Volume
50
Issue
42
Start Page
9969
End Page
9972
Copyright (Published Version)
2011 Wiley
Language
English
Status of Item
Peer reviewed
This item is made available under a Creative Commons License
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Name
acie_201104073_ms.pdf
Size
557.89 KB
Format
Adobe PDF
Checksum (MD5)
b761964e4d49e797197bbf72170ee59f
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