Options
Mechanical characterization of brain tissue in compression at dynamic strain rates
File(s)
File | Description | Size | Format | |
---|---|---|---|---|
JMBBM-D-12-00145 Tension paper(done) - Revised.pdf | 490.41 KB |
Date Issued
June 2012
Date Available
27T12:13:33Z September 2013
Abstract
Traumatic brain injury (TBI) occurs when local mechanical load exceeds certain tolerance levels for brain tissue. Extensive research has been done previously for brain matter experiencing compression at quasistatic loading; however, limited data is available to model TBI under dynamic impact conditions. In this research, an experimental setup was developed to perform unconfined compression tests and stress relaxation tests at strain rates ≤90/s. The brain tissue showed a stiffer response with increasing strain rates, showing that hyperelastic models are not adequate. Specifically, the compressive nominal stress at 30% strain was 8.83 ± 1.94, 12.8 ± 3.10 and 16.0 ± 1.41 kPa (mean ± SD) at strain rates of 30, 60 and 90/s, respectively. Relaxation tests were also conducted at 10%–50% strain with the average rise time of 10 ms, which can be used to derive time dependent parameters. Numerical simulations were performed using one-term Ogden model with initial shear modulus μo=6.06±1.44, 9.44 ± 2.427 and 12.64 ± 1.227 kPa (mean ± SD) at strain rates of 30, 60 and 90/s, respectively. A separate set of bonded and lubricated tests were also performed under the same test conditions to estimate the friction coefficient μ, by adopting combined experimental–computational approach. The values of μ were 0.1 ± 0.03 and 0.15 ± 0.07 (mean ± SD) at 30 and 90/s strain rates, respectively, indicating that pure slip conditions cannot be achieved in unconfined compression tests even under fully lubricated test conditions. The material parameters obtained in this study will help to develop biofidelic human brain finite element models, which can subsequently be used to predict brain injuries under impact conditions.
Type of Material
Journal Article
Publisher
Elsevier
Journal
Journal of the Mechanical Behavior of Biomedical Materials
Volume
10
Start Page
23
End Page
38
Copyright (Published Version)
2012 Elsevier
Language
English
Status of Item
Peer reviewed
This item is made available under a Creative Commons License
Owning collection
Scopus© citations
186
Acquisition Date
Jun 4, 2023
Jun 4, 2023
Views
1550
Last Month
5
5
Acquisition Date
Jun 4, 2023
Jun 4, 2023
Downloads
496
Last Month
8
8
Acquisition Date
Jun 4, 2023
Jun 4, 2023