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  5. Is there a role for Placental Volume, Vasculature and Calcification in monitoring Post-term Pregnancies?
 
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Is there a role for Placental Volume, Vasculature and Calcification in monitoring Post-term Pregnancies?

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Author(s)
Moran, Mary 
Zombori, Gergely 
Ryan, John 
Downey, P. 
McAuliffe, Fionnuala M. 
Uri
http://hdl.handle.net/10197/7661
Date Issued
01 June 2014
Date Available
02T09:16:08Z June 2016
Abstract
Objectives: This study aims to assess if three dimensional power Doppler (3DPD) ultrasound of the placenta, evaluating placental volume, vascularisation, and blood flow in post-term pregnancies differs from normal. It also examines whether computer analysis identifies the increased calcification normally present in the placenta after 40 weeks. Methods: This was a prospective cohort study involving 50 women with post-term pregnancies. Gestational age (GA) ranged from 40-41+6 weeks gestation. 3DPD ultrasound was used to evaluate placental volume, vascularisation index (VI), flow index (FI) and vascularisation-flow index (VFI). Following each scan the percentage of calcification was also calculated, by computer analysis. Results were compared with previously determined normal values (36-40 weeks gestation) and correlated with Doppler values and placental histology. Results: Results showed that placental volume, VI, FI and VFI are not influenced by GA when the pregnancy has advanced beyond 40 weeks and that values are similar between post-term pregnancies and normal pregnancies between 36 and 40 weeks. Placental volume was seen to decrease in post-term pregnancies as the mean UtA PI increased (P=0.047).  FI was reduced in cases where chorangiosis was found at histology (P=0.033), identifying the increased vessel number associated with these cases. Computer analysis of placental calcification identified the increased calcification expected after 40 weeks, and also showed that calcification continues to increase between 40 and 42 weeks (P=0.029). Conclusion: This study suggests that 3DPD placental assessment may provide additional information, assisting clinicians in decision making in post-term pregnancies.
Type of Material
Journal Article
Publisher
BMJ Publishing Group
Journal
Archives of Disease in Childhood: Fetal and Neonatal Edition
Volume
99
Issue
1: A87
Copyright (Published Version)
2014 the Authors
Keywords
  • 3D Power Doppler

  • Placenta

  • Calcification

  • Post-term

DOI
10.1136/archdischild-2014-306576.247
Language
English
Status of Item
Peer reviewed
This item is made available under a Creative Commons License
https://creativecommons.org/licenses/by-nc-nd/3.0/ie/
Owning collection
Medicine Research Collection
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