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Modulating mucins makes melanin
Author(s)
Date Issued
2022-03
Date Available
2022-01-14T16:05:11Z
Abstract
The outermost layer of skin, the epidermis has evolved to provide a physical barrier of protection from harmful substances and invasion of pathogens. The skin barrier consists in part of highly glycosylated proteins called mucins and the epithelium. Epidermal homeostasis is maintained by the proliferation and differentiation of its basal layer keratinocytes that migrate to the superficial layer of the epidermis, and through its regulated inter-cellular communication with the pigment producing cells, the melanocytes.
Sponsorship
Science Foundation Ireland
Type of Material
Journal Article
Publisher
Wiley
Journal
British Journal of Dermatology
Volume
186
Issue
3
Start Page
388
End Page
389
Copyright (Published Version)
2021 British Association of Dermatologists
Subjects
Language
English
Status of Item
Peer reviewed
ISSN
0007-0963
This item is made available under a Creative Commons License
File(s)
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Name
Casalou and Tobin Mucins BJD 2021.pdf
Size
23.2 KB
Format
Adobe PDF
Checksum (MD5)
6a4d75b75c5ff874e21121274ca38941
Owning collection
Mapped collections