Synthetic Positron Emission Tomography Using Conditional-Generative Adversarial Networks for Healthy Bone Marrow Baseline Image Generation

A Conditional-Generative Adversarial Network has been used for a supervised image-to-image translation task which outputs a synthetic PET scan based on real patient CT data. The network is trained using only data of patients with healthy bone marrow metabolism. This allows for a patient specific synthetic healthy baseline scan to be produced. This can be used by a clinician for comparison to real PET data in the absence of a baseline scan or to aid in the diagnosis of conditions such as Multiple Myeloma which manifest as changes in bone marrow metabolism