Options
Quaternarized pdppz: synthesis, DNA-binding and biological studies of a novel dppz derivative that causes cellular death upon light irradiation.
Date Issued
2011
Date Available
2013-05-16T10:54:10Z
Abstract
The quaternarized pdppz derivative 1 was shown to bind strongly to DNA with concomitant changes in its ground and excited state photophysical properties. Furthermore, the compound also showed rapid cellular uptake, and induced apoptosis upon light irradiation in various cancer cell lines after 24 hours of incubation.
Type of Material
Journal Article
Publisher
RSC Publishing
Journal
Chemical communications (Cambridge, England)
Volume
47
Issue
2
Start Page
686
End Page
688
Copyright (Published Version)
2011, Royal Society of Chemistry
Language
English
Status of Item
Peer reviewed
This item is made available under a Creative Commons License
File(s)
Loading...
Name
2011_Naphthalimides_Chem_Comm.pdf
Size
450.64 KB
Format
Adobe PDF
Checksum (MD5)
c3b4b9a6ee4696a86f5f0ca752e6a958
Owning collection