An Audit of Neural Tube Defects in the Republic Of Ireland for 2012-2015
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|Title:||An Audit of Neural Tube Defects in the Republic Of Ireland for 2012-2015||Authors:||McDonnell, R.; Delany, V; O’Mahony, M.T.; Turner, Michael J.; et al.||Permanent link:||http://hdl.handle.net/10197/10366||Date:||14-Mar-2018||Online since:||2019-05-09T08:09:05Z||Abstract:||Neural tube defects (NTD) are potentially preventable in two-thirds of cases by periconceptional maternal Folic Acid (FA) supplementation. A national audit for the years 2009-11 showed no decline in NTD rates over twenty years. The aim of this national audit was to determine trends/rates and inform revision of national FA supplementation and food fortification strategies. Of 274,732 live and stillbirths there were 121(42.0%) cases of anencephaly, 136(47.2%) cases of spina bifida and 31(10.8%) cases of encephalocoele giving a total of 288 and overall rate of 1.05/1000 compared with 1.04/1000 in 2009-11(NS). In the 184 women where the information was available, only 29.9%(n=55) reported starting FA before pregnancy. The number of cases diagnosed antenatally was 91%(n=262) and 53%(n=154) were live-born. This audit confirms that over a generation, healthcare interventions have not succeeded in decreasing the number of pregnancies in Ireland complicated by NTD, and that revised strategies need to be developed and implemented.||Type of material:||Journal Article||Publisher:||Irish Medical Organisation||Journal:||Irish Medical Journal||Volume:||111||Issue:||3||Start page:||712||End page:||723||Copyright (published version):||2018 Irish Medical Journal||Keywords:||Neural tube defects (NTD); Folic Acid (FA); Stillbirths; Anencephaly; Spina bifida; Encephalocoele||Other versions:||http://imj.ie/an-audit-of-neural-tube-defects-in-the-republic-of-ireland-for-2012-2015/||Language:||en||Status of Item:||Peer reviewed|
|Appears in Collections:||Medicine Research Collection|
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