An Audit of Neural Tube Defects in the Republic Of Ireland for 2012-2015

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Title: An Audit of Neural Tube Defects in the Republic Of Ireland for 2012-2015
Authors: McDonnell, R.Delany, VO’Mahony, M.T.Turner, Michael al.
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Date: 14-Mar-2018
Online since: 2019-05-09T08:09:05Z
Abstract: Neural tube defects (NTD) are potentially preventable in two-thirds of cases by periconceptional maternal Folic Acid (FA) supplementation. A national audit for the years 2009-11 showed no decline in NTD rates over twenty years. The aim of this national audit was to determine trends/rates and inform revision of national FA supplementation and food fortification strategies. Of 274,732 live and stillbirths there were 121(42.0%) cases of anencephaly, 136(47.2%) cases of spina bifida and 31(10.8%) cases of encephalocoele giving a total of 288 and overall rate of 1.05/1000 compared with 1.04/1000 in 2009-11(NS). In the 184 women where the information was available, only 29.9%(n=55) reported starting FA before pregnancy. The number of cases diagnosed antenatally was 91%(n=262) and 53%(n=154) were live-born. This audit confirms that over a generation, healthcare interventions have not succeeded in decreasing the number of pregnancies in Ireland complicated by NTD, and that revised strategies need to be developed and implemented.
Type of material: Journal Article
Publisher: Irish Medical Organisation
Journal: Irish Medical Journal
Volume: 111
Issue: 3
Start page: 712
End page: 723
Copyright (published version): 2018 Irish Medical Journal
Keywords: Neural tube defects (NTD)Folic Acid (FA)StillbirthsAnencephalySpina bifidaEncephalocoele
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Language: en
Status of Item: Peer reviewed
Appears in Collections:Medicine Research Collection

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