Assessment of Executive Functions in Preschool Children with Sickle Cell Anemia
Files in This Item:
|Downes_JINS_Special_Issue_FINAL PUB.docx||70.6 kB||Unknown||Download|
|Title:||Assessment of Executive Functions in Preschool Children with Sickle Cell Anemia||Authors:||Downes, Michelle
Kirkham, Fenella J.
Telfer, Paul T.
De Haan, Michelle
|Permanent link:||http://hdl.handle.net/10197/10452||Date:||30-May-2018||Online since:||2019-05-15T08:12:29Z||Abstract:||Objectives: Children with sickle cell anemia (SCA) are commonly reported to experience executive dysfunction. However, the development of executive function (EF) in preschool-age children without stroke in this patient population has not been investigated so it is unclear when and how these deficits emerge. Methods: This case-control study examines the feasibility of assessing the early development of executive functioning in 22 preschool children years with SCA in the domains of processing speed, working memory, attention, inhibitory control, and cognitive flexibility, as well as everyday function, in comparison to matched control children. Results: A pattern of potential deficits in early emerging executive skills was observed in the domains of inhibitory control and cognitive flexibility. Parents reported no differences for everyday EF and no significant differences were observed for working memory and processing speed. Conclusions: Results suggest that deficits in everyday executive difficulties, working memory, and processing speed, as commonly reported for older children with SCA, may not yet have emerged at this early developmental stage, despite specific deficits in cognitive flexibility and inhibitory control on behavioral measures. The feasibility of using available executive measures with preschool age children to characterize the development of early EF skills is discussed.||Type of material:||Journal Article||Publisher:||Cambridge University Press||Journal:||Journal of the International Neuropsychological Society||Volume:||24||Issue:||9||Start page:||949||End page:||954||Copyright (published version):||2018 The International Neuropsychological Society||Keywords:||Cognition; Executive function; Sickle cell disease; Preschool; Attention; Cognitive flexibility||DOI:||10.1017/S1355617718000255||Language:||en||Status of Item:||Peer reviewed|
|Appears in Collections:||Psychology Research Collection|
Show full item record
This item is available under the Attribution-NonCommercial-NoDerivs 3.0 Ireland. No item may be reproduced for commercial purposes. For other possible restrictions on use please refer to the publisher's URL where this is made available, or to notes contained in the item itself. Other terms may apply.