Epithelium-on Corneal Cross-linking for Progressive Keratoconus: Two-year Outcomes

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Title: Epithelium-on Corneal Cross-linking for Progressive Keratoconus: Two-year Outcomes
Authors: Cummings, Arthur B.Shaw, Parker J.Kelly, Gabrielle E.
Permanent link: http://hdl.handle.net/10197/10954
Date: Dec-2018
Online since: 2019-08-06T07:03:50Z
Abstract: Corneal cross-linking (CXL) has been established as a successful treatment tool for the treatment of progressive keratoconus in terms of slowing or halting progressive corneal steepening and thinning and even on some occasions, reversing the steepening. To date the Dresden epithelium-off protocol is regarded as the gold standard and the epithelium-on (epi-on) approaches have met with less success. Both doctors and patients would welcome an epi-on CXL procedure that provided good outcomes as the morbidity with epi-on CXL is so much less and the safety is enhanced. Patient comfort is greater with the epi-on techniques when compared to epi-off. This study looked at 82 eyes that had documented progression of keratoconus and then underwent epi-on CXL using the CXLO system. The results show that corneal steepening can be halted and even reversed over a 2-year follow-up period with no complications noted. Over the 24 months post treatment on average there was a decrease in all keratometry values, BAD and ISV when compared to before treatment with IHD being marginally increased. Further studies over a longer follow-up period are required but recent publications using the same approach are validating the findings seen in this study.
Type of material: Journal Article
Publisher: Jaypee Brothers Medical Publishing
Journal: International Journal of Keratoconus and Ectatic Corneal Diseases
Volume: 7
Issue: 2
Start page: 110
End page: 114
Keywords: Accelerated corneal cross-linkingBlurred visionCorneal cross-linkingCorneal ectasiaCorneal tomographyCorneal topographyCorneal transplantEye rubbingFemtosecond-laser assisted DALKKeratoconusSteep corneasQuality of visionVogt’s striae
DOI: 10.5005/jp-journals-10025-1166
Language: en
Status of Item: Peer reviewed
Appears in Collections:Mathematics and Statistics Research Collection

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