Anatomically accurate model of EMG during index finger flexion and abduction derived from diffusion tensor imaging

DC FieldValueLanguage
dc.contributor.authorBotelho, Diego Pereira-
dc.contributor.authorCurran, Kathleen M.-
dc.contributor.authorLowery, Madeleine M.-
dc.date.accessioned2020-02-13T15:20:24Z-
dc.date.available2020-02-13T15:20:24Z-
dc.date.copyright2019 the Authorsen_US
dc.date.issued2019-08-29-
dc.identifier.citationPLoS Computational Biologyen_US
dc.identifier.urihttp://hdl.handle.net/10197/11285-
dc.description.abstractThis study presents a modelling framework in which information on muscle fiber direction and orientation during contraction is derived from diffusion tensor imaging (DTI) and incorporated in a computational model of the surface electromyographic (EMG) signal. The proposed model makes use of the principle of reciprocity to simultaneously calculate the electric potentials produced at the recording electrode by charges distributed along an arbitrary number of muscle fibers within the muscle, allowing for a computationally efficient evaluation of extracellular motor unit action potentials. The approach is applied to the complex architecture of the first dorsal interosseous (FDI) muscle of the hand to simulate EMG during index finger flexion and abduction. Using diffusion tensor imaging methods, the results show how muscle fiber orientation and curvature in this intrinsic hand muscle change during flexion and abduction. Incorporation of anatomically accurate muscle architecture and other hand tissue morphologies enables the model to capture variations in extracellular action potential waveform shape across the motor unit population and to predict experimentally observed differences in EMG signal features when switching from index finger abduction to flexion. The simulation results illustrate how structural and electrical properties of the tissues comprising the volume conductor, in combination with fiber direction and curvature, shape the detected action potentials. Using the model, the relative contribution of motor units of different sizes located throughout the muscle under both conditions is examined, yielding a prediction of the detection profile of the surface EMG electrode array over the muscle cross-section.en_US
dc.description.sponsorshipEuropean Research Councilen_US
dc.format.mediumElectronic-eCollection-
dc.language.isoenen_US
dc.publisherPLoSen_US
dc.rightsThis is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_US
dc.subjectBioengineeringen_US
dc.subjectElectromyographyen_US
dc.subjectMuscle fibersen_US
dc.subjectElectrode potentialsen_US
dc.subjectAction potentialsen_US
dc.subjectHandsen_US
dc.subjectAnisotropyen_US
dc.titleAnatomically accurate model of EMG during index finger flexion and abduction derived from diffusion tensor imagingen_US
dc.typeJournal Articleen_US
dc.internal.authorcontactotheraoife.ogorman@ucd.ieen_US
dc.statusPeer revieweden_US
dc.identifier.volume15en_US
dc.identifier.issue8en_US
dc.identifier.startpagee1007267en_US
dc.identifier.doi10.1371/journal.pcbi.1007267-
dc.neeo.contributorBotelho|Diego Pereira|aut|-
dc.neeo.contributorCurran|Kathleen M.|aut|-
dc.neeo.contributorLowery|Madeleine M.|aut|-
dc.date.updated2019-12-12T10:55:08Z-
dc.identifier.grantid2014-CoG-646923-
item.grantfulltextopen-
item.fulltextWith Fulltext-
Appears in Collections:Electrical and Electronic Engineering Research Collection
Files in This Item:
File Description SizeFormat 
Botelho et al 2019.pdf3.59 MBAdobe PDFDownload
Show simple item record

SCOPUSTM   
Citations 50

1
checked on Feb 20, 2020

Page view(s)

166
checked on Feb 28, 2020

Download(s)

10
checked on Feb 28, 2020

Google ScholarTM

Check

Altmetric


This item is available under the Attribution-NonCommercial-NoDerivs 3.0 Ireland. No item may be reproduced for commercial purposes. For other possible restrictions on use please refer to the publisher's URL where this is made available, or to notes contained in the item itself. Other terms may apply.