Influence of Cu supplementation on toxic and essential trace element status in intensive reared beef cattle

Title: Influence of Cu supplementation on toxic and essential trace element status in intensive reared beef cattle
Authors: García-Vaquero, MarcoLópez-Alonso, MartaBenedito, José LuisHernández, JoaquinGutiérrez, BetianaMiranda, Marta
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Date: Dec-2011
Online since: 2020-03-06T12:08:07Z
Abstract: The aim of this study is to evaluate if dietary Cu supplementation that leads to a hepatic Cu accumulation over the normal range has an influence on trace element status that could contribute to the pathogenesis of other mineral related disorders. Samples (liver, kidney, spleen, diaphragm and brain) of beef calves receiving typical commercial diets Cu supplemented and non-supplemented were tested for differences in non-essential and essential trace elements determined by ICP-MS. As (kidney and diaphragm), Hg (liver and kidney), and Pb (liver, kidney and spleen) were significantly lower, while Cd residues (liver and kidney) were significantly higher in the Cu supplemented group. Mn and Ni significantly decreased and Mo increased in the brain, and Se (diaphragm) decreased in the Cu supplemented group. These interactions are unknown, and possibly with more than two metals involved as suggested in the case of the ratio Se:Cu in the animals of this study. The possible role of Cu supplementation on the status of certain metals associated to neurological diseases (Mn-Ni) in the brain deserves further investigation. Finally new research on Cu-Se supplementation is necessary to better understand the risk of the animals to suffer from Se deficiency.
metadata.dc.description.othersponsorship: Xunta de Galicia
Fondo Social Europeo
Type of material: Journal Article
Publisher: Elsevier
Journal: Food and Chemical Toxicology
Volume: 49
Issue: 12
Start page: 3358
End page: 3366
Copyright (published version): 2011 Elsevier
Keywords: DiaphragmLiverKidneyBrainSpleenAnimalsCattleArsenicSeleniumCopperLeadMercuryDietDietary supplementsMeat
DOI: 10.1016/j.fct.2011.09.013
Language: en
Status of Item: Peer reviewed
Appears in Collections:Agriculture and Food Science Research Collection

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