Potential of food intake biomarkers in nutrition research

DC FieldValueLanguage
dc.contributor.authorMcNamara, Aoife E.-
dc.contributor.authorBrennan, Lorraine-
dc.date.accessioned2020-06-23T11:47:24Z-
dc.date.available2020-06-23T11:47:24Z-
dc.date.copyright2020 the Authorsen_US
dc.date.issued2020-05-26-
dc.identifier.citationProceedings of the Nutrition Societyen_US
dc.identifier.issn0029-6651-
dc.identifier.urihttp://hdl.handle.net/10197/11396-
dc.description.abstractThe influence of dietary habits on health/disease is well-established. Accurate dietary assessment is essential to understand metabolic pathways/processes involved in this relationship. In recent years, biomarker discovery has become a major area of interest for improving dietary assessment. Well-established nutrient intake biomarkers exist, however, there is growing interest in identifying and using biomarkers for more accurate and objective measurements of food intake. Metabolomics has emerged as a key tool used for biomarker discovery, employing techniques such as nuclear magnetic resonance spectroscopy, or mass-spectrometry. To date, a number of putatively identified biomarkers were discovered for foods including meat, cruciferous vegetables and legumes. However, many of the results are associations only and lack the desired validation including dose-response studies. Food intake biomarkers can be employed to classify individuals into consumers/ non-consumers of specific foods or, into dietary patters. Food intake biomarkers can play a role in correcting self-reported measurement error, thus improving dietary intake estimates. Quanitification of food intake was previously performed for citrus (proline betaine), chicken (guanidoacetate) and grape (tartaric acid) intake. However, this area still requires more investigation and expansion to a range of foods. The present review will assess current literature of identified specific food intake biomarkers, their validation and the variety of biomarker uses. Addressing utility of biomarkers and highlighting gaps in this area is important to advance the field in the context of nutrition research.en_US
dc.description.sponsorshipEuropean Commission Horizon 2020en_US
dc.language.isoenen_US
dc.publisherCambridge University Pressen_US
dc.rightsThis article has been published in a revised form in Proceedings of the Nutrition Society https://doi.org/10.1017/S0029665120007053. This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. © the Authors.en_US
dc.subjectBiomarkersen_US
dc.subjectDietary assessmenten_US
dc.subjectFood intakeen_US
dc.subjectMetabolomicsen_US
dc.titlePotential of food intake biomarkers in nutrition researchen_US
dc.typeJournal Articleen_US
dc.internal.authorcontactothermaria.markiewicz-keszycka1@ucd.ieen_US
dc.statusPeer revieweden_US
dc.identifier.startpage1en_US
dc.identifier.endpage26en_US
dc.check.date2020-12-12-
dc.identifier.doi10.1017/s0029665120007053-
dc.neeo.contributorMcNamara|Aoife E.|aut|-
dc.neeo.contributorBrennan|Lorraine|aut|-
dc.date.embargo2020-11-26en_US
dc.description.adminUpdate citation details during checkdate report - ACen_US
dc.date.updated2020-06-04T16:46:48Z-
dc.identifier.grantid647783-
item.grantfulltextembargo_20201126-
item.fulltextWith Fulltext-
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Institute of Food and Health Research Collection
Agriculture and Food Science Research Collection
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