Comparative ocular gene therapy: How curing inherited blindness in Briard dogs benefits everyone

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Title: Comparative ocular gene therapy: How curing inherited blindness in Briard dogs benefits everyone
Authors: Reynolds, Alison
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Date: 11-Aug-2019
Online since: 2021-03-12T11:58:40Z
Abstract: Laboratory animals (zebrafish, rodents, rabbits, dogs and primates) have been used for decades to model various forms of ocular disease and in the discovery and development of therapeutics. Leber congenital amaurosis (LCA, OMIM # 20400) is a family of rare, inherited, early-onset severe retinal degenerations (EOSRDs) which affects 1 in 80,000 and presents in infancy.
Funding Details: University College Dublin
Type of material: Conference Publication
Copyright (published version): 2020 the Author
Keywords: Congenital blindnessGene therapyGene therapy productsLuxturnaVoretigene neparvovec
DOI: 10.1111/joa.13163
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Language: en
Status of Item: Peer reviewed
Conference Details: The 19th International Federation of Associations of Ananatomists (IFAA) Congress, London, United Kingdom, 9-11 August 2019
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Appears in Collections:Conway Institute Research Collection
Veterinary Medicine Research Collection

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