Structure-activity relationship of a novel family of cysteinyl leukotriene receptor antagonist quinoline compounds with anti-angiogenic activity

DC FieldValueLanguage
dc.contributor.authorReynolds, Alison-
dc.contributor.authorVentosa, Pilar-
dc.contributor.authorGranander, Johan-
dc.contributor.authorKilty, Claire-
dc.contributor.authorYoung, Elizabeth-
dc.contributor.authorButler, Clare T.-
dc.contributor.authorGalvin, Orla-
dc.contributor.authorMerrigan, Stephanie-
dc.contributor.authorSasore, Temitope-
dc.contributor.authorFernandez, Yolanda-
dc.contributor.authorGilheany, Declan G.-
dc.contributor.authorKennedy, Breandán-
dc.date.accessioned2021-11-09T13:09:19Z-
dc.date.available2021-11-09T13:09:19Z-
dc.date.issued2017-04-01-
dc.identifier.citationpA2 Onlineen_US
dc.identifier.issn1741-1157-
dc.identifier.urihttp://hdl.handle.net/10197/12596-
dc.descriptionPharacology 2016, London, United Kingdom, 13-15 December 2016en_US
dc.description.abstractIntroduction: Previously, we identified quininib (2-[(E)-2-(quinolin-2-yl)vinyl]phenol), a cysteinyl leukotriene receptor antagonist with anti-angiogenic and anti-permeable activity (1,2). Here, we report a structure activity relationship study to more comprehensively characterise features which confer anti-angiogenic activity.en_US
dc.language.isoenen_US
dc.publisherBritish Pharmacological Societyen_US
dc.subjectCysteinyl leukotriene receptor antagonistsen_US
dc.subjectAnti-angiogenic activityen_US
dc.subjectBlindnessen_US
dc.subjectCanceren_US
dc.subjectArthritisen_US
dc.subjectQuinoline compoundsen_US
dc.titleStructure-activity relationship of a novel family of cysteinyl leukotriene receptor antagonist quinoline compounds with anti-angiogenic activityen_US
dc.typeConference Publicationen_US
dc.internal.authorcontactotheralison.reynolds@ucd.ieen_US
dc.internal.webversionshttp://www.pa2online.org/abstract/abstract.jsp?abid=33289-
dc.statusPeer revieweden_US
dc.identifier.volume16en_US
dc.identifier.issue1en_US
dc.citation.otherAbstract Number: 200Pen_US
dc.neeo.contributorReynolds|Alison|aut|-
dc.neeo.contributorVentosa|Pilar|aut|-
dc.neeo.contributorGranander|Johan|aut|-
dc.neeo.contributorKilty|Claire|aut|-
dc.neeo.contributorYoung|Elizabeth|aut|-
dc.neeo.contributorButler|Clare T.|aut|-
dc.neeo.contributorGalvin|Orla|aut|-
dc.neeo.contributorMerrigan|Stephanie|aut|-
dc.neeo.contributorSasore|Temitope|aut|-
dc.neeo.contributorFernandez|Yolanda|aut|-
dc.neeo.contributorGilheany|Declan G.|aut|-
dc.neeo.contributorKennedy|Breandán|aut|-
dc.date.updated2020-09-15T17:01:32Z-
dc.rights.licensehttps://creativecommons.org/licenses/by-nc-nd/3.0/ie/en_US
item.fulltextWith Fulltext-
item.grantfulltextopen-
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