Continuous flow photochemistry for the preparation of bioactive molecules

DC FieldValueLanguage
dc.contributor.authorDi Filippo, Mara-
dc.contributor.authorBracken, Cormac-
dc.contributor.authorBaumann, Marcus-
dc.date.accessioned2021-11-09T15:50:03Z-
dc.date.available2021-11-09T15:50:03Z-
dc.date.copyright2020 the Authorsen_US
dc.date.issued2020-01-15-
dc.identifier.citationMoleculesen_US
dc.identifier.issn1420-3049-
dc.identifier.urihttp://hdl.handle.net/10197/12599-
dc.description.abstractThe last decade has witnessed a remarkable development towards improved and new photochemical transformations in response to greener and more sustainable chemical synthesis needs. Additionally, the availability of modern continuous flow reactors has enabled widespread applications in view of more streamlined and custom designed flow processes. In this focused review article, we wish to evaluate the standing of the field of continuous flow photochemistry with a specific emphasis on the generation of bioactive entities, including natural products, drugs and their precursors. To this end we highlight key developments in this field that have contributed to the progress achieved to date. Dedicated sections present the variety of suitable reactor designs and set-ups available; a short discussion on the relevance of greener and more sustainable approaches; and selected key applications in the area of bioactive structures. A final section outlines remaining challenges and areas that will benefit from further developments in this fast-moving area. It is hoped that this report provides a valuable update on this important field of synthetic chemistry which may fuel developments in the future.en_US
dc.description.sponsorshipUniversity College Dublinen_US
dc.format.mediumElectronic-
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.rightsThis is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.subjectContinuous flow chemistryen_US
dc.subjectPhotochemistryen_US
dc.subjectPhotocatalysisen_US
dc.subjectBioactive moleculesen_US
dc.subjectMedicinal chemistryen_US
dc.subjectProcess developmenten_US
dc.subjectEnabling technologiesen_US
dc.subjectLighten_US
dc.subjectReactoren_US
dc.subjectPhotooxygenationen_US
dc.subjectVitamin D-3en_US
dc.subjectOxidationsen_US
dc.titleContinuous flow photochemistry for the preparation of bioactive moleculesen_US
dc.typeJournal Articleen_US
dc.internal.authorcontactothermarcus.baumann@ucd.ieen_US
dc.statusPeer revieweden_US
dc.identifier.volume25en_US
dc.identifier.issue2en_US
dc.citation.otherArticle Number: 356en_US
dc.identifier.doi10.3390/molecules25020356-
dc.neeo.contributorDi Filippo|Mara|aut|-
dc.neeo.contributorBracken|Cormac|aut|-
dc.neeo.contributorBaumann|Marcus|aut|-
dc.date.updated2020-09-21T18:16:20Z-
dc.rights.licensehttps://creativecommons.org/licenses/by/3.0/ie/en_US
item.fulltextWith Fulltext-
item.grantfulltextopen-
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