Comment on: Metabolic surgery improves renal injury independent of weight loss: a meta-analysis

Files in This Item:
 File SizeFormat
DownloadSOARD editorial 190328 no highlighting.docx82.88 kBUnknown
Title: Comment on: Metabolic surgery improves renal injury independent of weight loss: a meta-analysis
Other Titles: Weight-independent reductions in proteinuria after metabolic surgery: implications for therapy development and treatment algorithms in diabetic kidney disease
Authors: Martin, William P.le Roux, Carel W.
Permanent link:
Date: 1-Jun-2019
Online since: 2021-11-29T11:40:39Z
Abstract: Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease and significantly elevates cardiovascular disease risk [1]. Persons with DKD accounted for 45.4% and 38.2% of incident and prevalent cases of end-stage renal disease in the United States in 2015, respectively [2]. Current management of DKD focuses on control of hyperglycemia and hypertension along with renin-angiotensin-aldosterone system blockade to minimize proteinuria. The most notable recent advances in DKD care include sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide-1 agonists, which reduce glycosylated hemoglobin (A1C), blood pressure, weight, cardiovascular mortality, and nephropathy progression [ 3]. Despite this, existing therapies for DKD slow the rate of renal functional decline rather than reversing it.
Funding Details: Health Research Board
Wellcome Trust
Type of material: Journal Article
Publisher: Elsevier
Journal: Surgery for Obesity and Related Diseases
Volume: 15
Issue: 6
Start page: 1020
End page: 1023
Copyright (published version): 2019 American Society for Bariatric Surgery
Keywords: KidneyHumansMorbid obesityWeight lossBariatric Surgery
DOI: 10.1016/j.soard.2019.04.001
Language: en
Status of Item: Peer reviewed
ISSN: 1550-7289
This item is made available under a Creative Commons License:
Appears in Collections:Conway Institute Research Collection
Medicine Research Collection

Show full item record

Page view(s)

Last Week
Last month
checked on Jan 19, 2022


checked on Jan 19, 2022

Google ScholarTM



If you are a publisher or author and have copyright concerns for any item, please email and the item will be withdrawn immediately. The author or person responsible for depositing the article will be contacted within one business day.