Modulating mucins makes melanin

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Title: Modulating mucins makes melanin
Authors: Casalou, CristinaTobin, Desmond John
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Date: 24-Nov-2021
Online since: 2022-01-14T16:05:11Z
Abstract: The outermost layer of skin, the epidermis has evolved to provide a physical barrier of protection from harmful substances and invasion of pathogens. The skin barrier consists in part of highly glycosylated proteins called mucins and the epithelium. Epidermal homeostasis is maintained by the proliferation and differentiation of its basal layer keratinocytes that migrate to the superficial layer of the epidermis, and through its regulated inter-cellular communication with the pigment producing cells, the melanocytes.
Funding Details: Science Foundation Ireland
Type of material: Journal Article
Publisher: Wiley
Journal: British Journal of Dermatology
Copyright (published version): 2021 British Association of Dermatologists
Keywords: DermatologySkin pigmentation
DOI: 10.1111/bjd.20877
Language: en
Status of Item: Peer reviewed
ISSN: 0007-0963
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Appears in Collections:Conway Institute Research Collection
Medicine Research Collection

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