Exploring the translational challenge for medical applications of ionising radiation and corresponding radiation protection research

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Title: Exploring the translational challenge for medical applications of ionising radiation and corresponding radiation protection research
Authors: Bockhold, SophieFoley, Shane J.Rainford, Louise A.McNulty, Jonathan P.
Permanent link: http://hdl.handle.net/10197/12792
Date: 18-Mar-2022
Online since: 2022-03-31T15:22:32Z
Abstract: Background: Medical applications of ionising radiation and associated radiation protection research often encounter long delays and inconsistent implementation when translated into clinical practice. A coordinated effort is needed to analyse the research needs for innovation transfer in radiation-based high-quality healthcare across Europe which can inform the development of an innovation transfer framework tailored for equitable implementation of radiation research at scale. Methods: Between March and September 2021 a Delphi methodology was employed to gain consensus on key translational challenges from a range of professional stakeholders. A total of three Delphi rounds were conducted using a series of electronic surveys comprised of open-ended and closed-type questions. The surveys were disseminated via the EURAMED Rocc-n-Roll consortium network and prominent medical societies in the field. Approximately 350 professionals were invited to participate. Participants’ level of agreement with each generated statement was captured using a 6-point Likert scale. Consensus was defined as median ≥ 4 with ≥ 60% of responses in the upper tertile of the scale. Additionally, the stability of responses across rounds was assessed. Results: In the first Delphi round a multidisciplinary panel of 20 generated 127 unique statements. The second and third Delphi rounds recruited a broader sample of 130 individuals to rate the extent to which they agreed with each statement as a key translational challenge. A total of 60 consensus statements resulted from the iterative Delphi process of which 55 demonstrated good stability. Ten statements were identified as high priority challenges with ≥ 80% of statement ratings either ‘Agree’ or ‘Strongly Agree’. Conclusion: A lack of interoperability between systems, insufficient resources, unsatisfactory education and training, and the need for greater public awareness surrounding the benefits, risks, and applications of ionising radiation were identified as principal translational challenges. These findings will help to inform a tailored innovation transfer framework for medical radiation research.
Funding Details: European Commission Horizon 2020
Type of material: Journal Article
Publisher: Springer Science and Business Media LLC
Journal: Journal of Translational Medicine
Volume: 20
Copyright (published version): 2022 the Authors
Keywords: Clinical researchMedical innovationsClinical practiceDelphi studies
DOI: 10.1186/s12967-022-03344-4
Language: en
Status of Item: Peer reviewed
ISSN: 1479-5876
This item is made available under a Creative Commons License: https://creativecommons.org/licenses/by/3.0/ie/
Appears in Collections:Medicine Research Collection

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