Precursor-directed biosynthesis of fluorinated iturin A in Bacillus spp.
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|Title:||Precursor-directed biosynthesis of fluorinated iturin A in Bacillus spp.||Authors:||Moran, Stephen
Rai, Dilip K.
Clark, Benjamin R.
Murphy, Cormac D.
|Permanent link:||http://hdl.handle.net/10197/3700||Date:||2009||Abstract:||Some iturin A-producing strains of Bacillus subtilis will elaborate the novel fluorinated analogue when incubated with 3-fluoro-L-tyrosine. The activity of iturin A is dependent on the D-tyrosine residue and the presence of fluorotyrosine may result in an improvement of the biological properties of this lipopeptide. The fluorinated iturin might also be used as a probe for studying its interaction with biological membranes.||Funding Details:||Irish Research Council for Science, Engineering and Technology||Type of material:||Journal Article||Publisher:||RSC Publishing||Copyright (published version):||2009 the authors||Keywords:||Fluorine;Antibiotic||Subject LCSH:||Fluorine
|DOI:||10.1039/b816345f||Language:||en||Status of Item:||Peer reviewed|
|Appears in Collections:||Biomolecular and Biomedical Science Research Collection|
CSCB Research Collection
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