Incandescent Porous Carbon Microspheres to Light up Cells: Solution Phenomena and Cellular Uptake

DC FieldValueLanguage
dc.contributor.authorDuffy, Paul
dc.contributor.authorMagno, Luís M.
dc.contributor.authorYadavc, Rahul B.
dc.contributor.authorRoberts, Selene K.
dc.contributor.authorWard, Andrew D.
dc.contributor.authorBotchway, Stanley W.
dc.contributor.authorColavita, Paula E.
dc.contributor.authorQuinn, Susan J.
dc.date.accessioned2013-05-16T09:09:06Z
dc.date.available2013-05-16T09:09:06Z
dc.date.copyright2012, Royal Society of Chemistryen
dc.date.issued2012
dc.identifier.citationJournal of Materials Chemistryen
dc.identifier.urihttp://hdl.handle.net/10197/4320
dc.description.abstractCarbon based materials are attractive for biological applications because of their excellent biocompatibility profile. Porous carbons with high specific surface area are particularly interesting because it is possible in principle to leverage their properties to deliver high drug payloads. In this work, porous carbon microspheres with high specific surface area were prepared and studied in solution and in cells. Raman optical tweezer trapping of microspheres, excited by 532 nm, results in graphitization and incandescence in solvents that display poor heat conduction. Fluorescence confocal microscopy imaging was used to demonstrate the uptake of fluorescently labelled microspheres by cells and the ability to leverage their optical absorptivity in order to cause carbon graphitization and cell death.en
dc.description.sponsorshipScience Foundation Irelanden
dc.language.isoenen
dc.publisherRSC Publishingen
dc.subjectIntracellular delivery agents
dc.subjectRaman-optical tweezer studies
dc.subjectIncandescent emission
dc.subjectGraphitization
dc.titleIncandescent Porous Carbon Microspheres to Light up Cells: Solution Phenomena and Cellular Uptakeen
dc.typeJournal Articleen
dc.internal.authorcontactothersusan.quinn@ucd.ie
dc.internal.availabilityFull text availableen
dc.statusNot peer revieweden
dc.identifier.volume22en
dc.identifier.issue2en
dc.identifier.startpage432en
dc.identifier.endpage439en
dc.identifier.doi10.1039/C1JM14303D-
dc.neeo.contributorDuffy|Paul|aut|-
dc.neeo.contributorMagno|Luís M.|aut|-
dc.neeo.contributorYadavc|Rahul B.|aut|-
dc.neeo.contributorRoberts|Selene K.|aut|-
dc.neeo.contributorWard|Andrew D.|aut|-
dc.neeo.contributorBotchway|Stanley W.|aut|-
dc.neeo.contributorColavita|Paula E.|aut|-
dc.neeo.contributorQuinn|Susan J.|aut|-
dc.description.othersponsorshipEPA Irelanden
dc.description.adminRB 15/05/13en
dc.internal.rmsid271671556
dc.date.updated2013-04-26T17:54:10Z
dc.rights.licensehttps://creativecommons.org/licenses/by-nc-nd/3.0/ie/en
item.grantfulltextopen-
item.fulltextWith Fulltext-
Appears in Collections:Chemistry Research Collection
Files in This Item:
 File SizeFormat
Download2012__JMC_Quinn_Cells.pdf613.69 kBAdobe PDF
Show simple item record

SCOPUSTM   
Citations 20

26
Last Week
0
Last month
0
checked on Sep 12, 2020

Page view(s) 50

1,584
Last Week
3
Last month
13
checked on Aug 19, 2022

Download(s) 50

414
checked on Aug 19, 2022

Google ScholarTM

Check

Altmetric


If you are a publisher or author and have copyright concerns for any item, please email research.repository@ucd.ie and the item will be withdrawn immediately. The author or person responsible for depositing the article will be contacted within one business day.