Hippocampal contribution to vector model hypothesis during cue-dependent navigation
|Title:||Hippocampal contribution to vector model hypothesis during cue-dependent navigation||Authors:||Diviney, M.
|Permanent link:||http://hdl.handle.net/10197/4991||Date:||17-Jun-2013||Online since:||2013-11-28T14:46:03Z||Abstract:||Learning to navigate toward a goal is an essential skill. Place learning is thought to rely on the ability of animals to associate the location of a goal with surrounding environmental cues. Using the Morris water maze, a task popularly used to examine place learning, we demonstrate that distal cues provide animals with distance and directional information. We show how animals use the cues in a visually dependent guidance manner to find the goal. Further, we demonstrate how hippocampal lesions disrupt this learning mechanism. Our results can be explained through the vector model of navigation built on associative learning principles rather than evoking a cognitive map.||Type of material:||Journal Article||Publisher:||Cold Spring Harbor Laboratory Press||Journal:||Learning & Memory||Volume:||20||Issue:||7||Start page:||367||End page:||378||Copyright (published version):||2013 Cold Spring Harbor Laboratory Press||Keywords:||Hippocampus; vector model of navigation; associative learning||DOI:||10.1101/lm.029272.112||Language:||en||Status of Item:||Peer reviewed|
|Appears in Collections:||SBI Research Collection|
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