Imatinib-dependent tyrosine phosphorylation profiling of Bcr-Abl-positive chronic myeloid leukemia cells
|Title:||Imatinib-dependent tyrosine phosphorylation profiling of Bcr-Abl-positive chronic myeloid leukemia cells||Authors:||Preisinger, C.
Schwarz, J. P.
Bleijerveld, O. B.
|Permanent link:||http://hdl.handle.net/10197/5078||Date:||27-Aug-2012||Abstract:||Bcr-Abl is the major cause and pathogenetic principle of chronic myeloid leukemia (CML). Bcr-Abl results from a chromosomal translocation that fuses the bcr and abl genes, thereby generating a constitutively active tyrosine kinase, which stimulates several signaling networks required for proliferation and survival.||Type of material:||Journal Article||Publisher:||Nature Publishing Group||Copyright (published version):||2012 Nature Publishing Group||Keywords:||Bcr-Abl; chronic myeloid leukemia (CML)||DOI:||10.1038/leu.2012.243||Language:||en||Status of Item:||Peer reviewed|
|Appears in Collections:||SBI Research Collection|
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