Imatinib-dependent tyrosine phosphorylation profiling of Bcr-Abl-positive chronic myeloid leukemia cells
|Title:||Imatinib-dependent tyrosine phosphorylation profiling of Bcr-Abl-positive chronic myeloid leukemia cells||Authors:||Preisinger, C.
Schwarz, J. P.
Bleijerveld, O. B.
|Permanent link:||http://hdl.handle.net/10197/5078||Date:||27-Aug-2012||Abstract:||Bcr-Abl is the major cause and pathogenetic principle of chronic myeloid leukemia (CML). Bcr-Abl results from a chromosomal translocation that fuses the bcr and abl genes, thereby generating a constitutively active tyrosine kinase, which stimulates several signaling networks required for proliferation and survival.||Type of material:||Journal Article||Publisher:||Nature Publishing Group||Journal:||Leukemia||Volume:||27||Issue:||3||Start page:||743||End page:||746||Copyright (published version):||2012 Nature Publishing Group||Keywords:||Bcr-Abl; chronic myeloid leukemia (CML)||DOI:||10.1038/leu.2012.243||Language:||en||Status of Item:||Peer reviewed||metadata.dc.date.available:||2013-11-29T10:20:36Z|
|Appears in Collections:||SBI Research Collection|
Show full item record
Page view(s) 5057
This item is available under the Attribution-NonCommercial-NoDerivs 3.0 Ireland. No item may be reproduced for commercial purposes. For other possible restrictions on use please refer to the publisher's URL where this is made available, or to notes contained in the item itself. Other terms may apply.