Seroprevalence of Leptospira Hardjo in the Irish suckler cattle population

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Title: Seroprevalence of Leptospira Hardjo in the Irish suckler cattle population
Authors: Ryan, Eoin Gerard
Leonard, Nola
O'Grady, Luke
et al.
Permanent link: http://hdl.handle.net/10197/5765
Date: 2012
Abstract: Background: Prior to the present study, the seroprevalence of leptospirosis in Irish suckler herds was unknown. In this study, we describe the herd and animal-level prevalence of Leptospira Hardjo infection in the Irish suckler cattle population. For the purposes of the study, the 26 counties of the Republic of Ireland were divided into 6 regions from which a representative number of herds were selected. A herd was considered eligible for sampling if it was not vaccinating against leptospirosis and if it contained ≥ 9 breeding animals of beef breed ≥ 12 months of age. In total, 288 randomly selected herds were eligible for inclusion in the seroprevalence dataset analysis. Serological testing was carried out using a commercially available monoclonal antibody-capture ELISA, (sensitivity 100%; specificity 86.67%). Results: Herds were categorised as either “Free from Infection” or “Infected” using the epidemiological software tool, FreeCalc 2.0. Using this classification, 237 herds were “Infected” (82.29%). The South West and South East regions had the highest herd prevalence. The regional effect on herd prevalence was largely mirrored by breeding herd size. A true animal-level prevalence of 41.75% was calculated using the epidemiological software tool, TruePrev. There was a statistically significant regional trend, with true prevalence being highest in the South East (P < 0.05). The median Breeding Herd Size (BHS), when categorised into quartiles, had a statistically significant influence on individual animal true seroprevalence (P < 0.001); true seroprevalence increased with increasing BHS. Conclusions: Leptospirosis is a widespread endemic disease in the Republic of Ireland. It is possible that economic losses due to leptospirosis in unvaccinated Irish suckler herds may be underestimated.
Type of material: Journal Article
Publisher: Springer (Biomed Central Ltd.)
Copyright (published version): 2012 the author(s)
Keywords: Leptospirosis;Hardjo;Suckler;Ireland;Seroprevalence;ELISA;Herd size;Region;FreeCalc;Endemic
DOI: 10.1186/2046-0481-65-8
Language: en
Status of Item: Peer reviewed
Appears in Collections:Veterinary Medicine Research Collection
CVERA Research Collection

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