A high rate tension device for characterizing brain tissue

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Title: A high rate tension device for characterizing brain tissue
Authors: Rashid, Badar
Destrade, Michel
Gilchrist, M. D.
Permanent link: http://hdl.handle.net/10197/5920
Date: 8-Mar-2012
Abstract: The mechanical characterization of brain tissue at high loading velocities is vital for understanding and modeling traumatic brain injury. The most severe form of traumatic brain injury is diffuse axonal injury, which involves damage to individual nerve cells (neurons). Diffuse axonal injury in animals and humans occurs at strains >10% and strain rates >10 s−1. The mechanical properties of brain tissues at these strains and strain rates are of particular significance, as they can be used in finite element human head models to accurately predict brain injuries under different impact conditions. Existing conventional tensile testing machines can only achieve maximum loading velocities of 500 mm/min, whereas the Kolsky bar apparatus is more suitable for strain rates >100 s−1. In this study, a custom-designed high rate tension device is developed and calibrated to estimate the mechanical properties of brain tissue in tension at strain rates ≤ 90 s−1, while maintaining a uniform velocity. The range of strain can o be extended to 100% depending on the thickness of a sample. The same apparatus can be used to characterize the dynamic behavior of skin and other soft biological tissues by using appropriately sized load cells with a capacity of 10 N and above.
Type of material: Journal Article
Publisher: Sage Publications
Copyright (published version): 2012 Sage Publications
Keywords: Traumatic;Brain injury;Tensile;Shear;Strain;Axon;Impact
DOI: 10.1177/1754337112436900
Language: en
Status of Item: Peer reviewed
Appears in Collections:Mechanical & Materials Engineering Research Collection

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