Transition metal bioconjugates with an organometallic link between the metal and the biomolecular scaffold

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Title: Transition metal bioconjugates with an organometallic link between the metal and the biomolecular scaffold
Authors: Monney, Angèle
Albrecht, Martin
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Date: Sep-2013
Abstract: This overview compiles recent advances in the synthesis and application of organometallic bioconjugates that comprise a metal–carbon linkage between the metal and the biomolecular scaffold. This specific area of bioorganometallic chemistry has been spurred by the discovery of naturally occurring bioorganometallic compounds and afforded organometallic bioconjugates from transition metals binding to amino acids, nucleic acids and other biomolecules. These artificial bioorganometallic compounds have found application in various domains, including catalysis, medicinal chemistry, bioanalysis, and materials science.
Funding Details: European Research Council
Science Foundation Ireland
Type of material: Journal Article
Publisher: Elsevier
Journal: Coordination Chemistry Reviews
Volume: 257
Issue: 17-18
Start page: 2420
End page: 2433
Copyright (published version): 2013 Elsevier
Keywords: BioorganometallicsOrganometallicsBioconjugatesPeptidesN-heterocyclic carbenes
DOI: 10.1016/j.ccr.2012.12.015
Language: en
Status of Item: Peer reviewed
Appears in Collections:Chemistry Research Collection

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