Methyltransferase Activity of an Iridium Center with Methylpyridinium as Methylene Source
|Title:||Methyltransferase Activity of an Iridium Center with Methylpyridinium as Methylene Source||Authors:||Lalrempuia, Ralte
|Permanent link:||http://hdl.handle.net/10197/6830||Date:||10-Oct-2011||Online since:||2015-08-20T16:05:26Z||Abstract:||An iridium center transfers a methyl group from pyridinium to an aryl unit, using exclusively the pyridine-bound methyl group as a mild methylene source. The reaction also involves cleavage of an unactivated C(aryl)[BOND]H bond and nitrile solvent activation. The process is reminiscent of DNA methylation and entails the formation of two new C(sp2)[BOND]C(sp3) bonds within the metal coordination sphere (see scheme).||Funding Details:||European Research Council
Science Foundation Ireland
|Type of material:||Journal Article||Publisher:||Wiley||Journal:||Angewandte Chemie International Edition||Volume:||50||Issue:||42||Start page:||9969||End page:||9972||Copyright (published version):||2011 Wiley||Keywords:||Functional analogues; Iridium; Methyl transferase; Methylene transfer; Pyridinium||DOI:||10.1002/anie.201104073||Language:||en||Status of Item:||Peer reviewed|
|Appears in Collections:||Chemistry Research Collection|
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