Does regional anaesthesia and analgesia or opioid analgesia influence recurrence after primary cancer surgery? An update of available evidence

DC FieldValueLanguage
dc.contributor.authorAsh, Simon A.-
dc.contributor.authorBuggy, Donal J.-
dc.date.accessioned2017-01-03T17:09:29Z-
dc.date.available2017-01-03T17:09:29Z-
dc.date.copyright2013 Elsevieren
dc.date.issued2013-12-
dc.identifier.citationBest Practice and Research Clinical Anaesthesiologyen
dc.identifier.urihttp://hdl.handle.net/10197/8242-
dc.description.abstractCancer continues to be a key cause of morbidity and mortality worldwide and its overall incidence continues to increase. Anaesthetists are increasingly faced with the challenge of managing cancer patients, for surgical resection to debulk or excise the primary tumour, or for surgical emergencies in patients on chemotherapy or for the analgesic management of disease- or treatment-related chronic pain. Metastatic recurrence is a concern. Surgery and a number of perioperative factors are suspected to accelerate tumour growth and potentially increase the risk of metastatic recurrence. Retrospective analyses have suggested an association between anaesthetic technique and cancer outcomes, and anaesthetists have sought to ameliorate the consequences of surgical trauma and minimise the impact of anaesthetic interventions. Just how anaesthesia and analgesia impact cancer recurrence and consequent survival is very topical, as understanding the potential mechanisms and interactions has an impact on the anaesthetist's ability to contribute to the successful outcome of oncological interventions. The outcome of ongoing, prospective, randomized trials are awaited with interest.en
dc.language.isoenen
dc.publisherElsevieren
dc.rightsThis is the author’s version of a work that was accepted for publication in Best Practice and Research Clinical Anaesthesiology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Best Practice and Research Clinical Anaesthesiology (VOL 27, ISSUE 4, (2013)) DOI: 10.1016/j.bpa.2013.10.005.en
dc.subjectAnaesthesiaen
dc.subjectMetastasesen
dc.subjectRecurrenceen
dc.subjectCanceren
dc.subjectRegionalen
dc.subjectOpioidsen
dc.subjectNSAIDsen
dc.titleDoes regional anaesthesia and analgesia or opioid analgesia influence recurrence after primary cancer surgery? An update of available evidenceen
dc.typeBook Chapteren
dc.internal.authorcontactotherdonal.buggy@ucd.ie-
dc.statusPeer revieweden
dc.identifier.volume27en
dc.identifier.issue4en
dc.identifier.startpage441en
dc.identifier.endpage456en
dc.identifier.doi10.1016/j.bpa.2013.10.005-
dc.neeo.contributorAsh|Simon A.|aut|-
dc.neeo.contributorBuggy|Donal J.|aut|-
dc.internal.rmsid368737576-
dc.date.updated2016-12-19T15:14:24Z-
dc.rights.licensehttps://creativecommons.org/licenses/by-nc-nd/3.0/ie/en
item.grantfulltextopen-
item.fulltextWith Fulltext-
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