Advances in magnetic tweezers for single molecule and cell biophysics

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Title: Advances in magnetic tweezers for single molecule and cell biophysics
Authors: Kilinc, Devrim
Lee, Gil U.
Permanent link: http://hdl.handle.net/10197/8459
Date: Nov-2014
Abstract: Magnetic tweezers (MTW) enable highly accurate forces to be transduced to molecules to study mechanotransduction at the molecular or cellular level. We review recent MTW studies in single molecule and cell biophysics that demonstrate the flexibility of this technique. We also discuss technical advances in the method on several fronts, i.e., from novel approaches for the measurement of torque to multiplexed biophysical assays. Finally, we describe multi-component nanorods with enhanced optical and magnetic properties and discuss their potential as future MTW probes.
Funding Details: European Commission - European Regional Development Fund
Higher Education Authority
Science Foundation Ireland
Type of material: Journal Article
Publisher: Royal Society of Chemistry
Copyright (published version): 2014 The Royal Society of Chemistry
Keywords: Magnetic tweezers;Magnetic nanorods;Biophysical tools;Technical advances
DOI: 10.1039/c3ib40185e
Language: en
Status of Item: Peer reviewed
Appears in Collections:Medicine Research Collection

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