Improving Biopharmaceutical Manufacturing Yield Using Neural Network Classification

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Title: Improving Biopharmaceutical Manufacturing Yield Using Neural Network Classification
Authors: Fahey, Will
Carroll, Paula
Permanent link: http://hdl.handle.net/10197/8746
Date: Jan-2016
Abstract: Traditionally, the Six Sigma framework has underpinned quality improvement and assurance in biopharmaceutical manufacturing process management. This paper proposes a neural network (NN) approach to vaccine yield classification and compares it to an existing multiple linear regression approach. As part of the Six Sigma process, this paper shows how a data mining framework can be used to extract further value and insight from the data gathered during the manufacturing process, and how insights into yield classification can be used in the quality improvement process.
Type of material: Journal Article
Publisher: BioProcessing Journal
Keywords: Biopharmaceutical manufacturing;Neural network;Classification;Business analyitics
DOI: 10.12665/J144.Carroll
Language: en
Status of Item: Peer reviewed
Appears in Collections:Business Research Collection

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