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Metabolomics in nutrition research – a powerful window into nutritional metabolism
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| Title: | Metabolomics in nutrition research – a powerful window into nutritional metabolism | Authors: | Brennan, Lorraine | Permanent link: | http://hdl.handle.net/10197/9147 | Date: | Jan-2017 | Online since: | 2018-01-08T10:48:55Z | Abstract: | Metabolomics is the study of small molecules present in biological samples. In recent years it has become evident that such small molecules, called metabolites, play a key role in the development of disease states. Furthermore, metabolomic applications can reveal information about alterations in certain metabolic pathways under different conditions. Data acquisition in metabolomics is usually performed using nuclear magnetic resonance (NMR)-based approaches or mass spectrometry (MS)-based approaches with a more recent trend including the application of multiple platforms in order to maximise the coverage in terms of metabolites measured. The application of metabolomics is rapidly increasing and the present review will highlight applications in nutrition research. | Funding Details: | European Research Council Science Foundation Ireland |
Type of material: | Journal Article | Publisher: | Portland Press | Journal: | Essays in Biochemistry | Volume: | 60 | Issue: | 5 | Start page: | 451 | End page: | 458 | Copyright (published version): | 2016 the Authors | Keywords: | Metabolomics; Metabolites; Nutrition; LC-MS; NMR; GC-MS | DOI: | 10.1042/EBC20160029 | Language: | en | Status of Item: | Peer reviewed | This item is made available under a Creative Commons License: | https://creativecommons.org/licenses/by-nc-nd/3.0/ie/ |
| Appears in Collections: | Institute of Food and Health Research Collection Agriculture and Food Science Research Collection |
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